6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Basic information
Product Name:6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride
Synonyms:4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINE;ASINEX-REAG BAS 13549338;6--3-(4-)-1,2 KY-16-05;Paliperidone Related CoMpound B;1,2-Benzisoxazole,6-fluoro-3-(4-piperidinyl)-, hydrochloride (1:1);Paliperidone int 2;Paliperidone Related Compound B (20 mg) (6-fluoro-3-(piperidin-4-yl)benzoisoxazole hydrochloride);Iloperidone intermediate
CAS:84163-13-3
MF:C12H14ClFN2O
MW:256.7
EINECS:700-303-4
Product Categories:APIs Intermediate;Iloperidone Intermediate;Oxazole&Isoxazole;(intermediate of risperidone)
Mol File:84163-13-3.mol
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Structure
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Chemical Properties
Melting point 293-295 °C
density 1.42g/cm3 at 20℃
vapor pressure 0.002-0.005Pa at 20-25℃
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly, Heated)
form Solid
color White to Off-White
LogP-0.84 at 20℃ and pH7
CAS DataBase Reference84163-13-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
HazardClass IRRITANT
HS Code 2934990002
MSDS Information
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Usage And Synthesis
Uses6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Hydrochloride (Risperidone EP Impurity M; Paliperidone USP Related Compound B) is a novel antiproliferative agent.
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-7-methoxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Ocaperidone Diphenoxylate 5-FLUORO-3-(4-PIPERIDINYL)-1,2-BENZISOXAZOLE HYDROCHLORIDE Topotecan hydrochloride Isoxazole 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole METHYL RISPERIDONE ILOPERIDONE Benperidol 7-HYDROXY RISPERIDONE ABAPERIDONE Haloperidol fluoro jade Risperidone DROPERIDOL Paliperidone

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