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| | PINOSYLVIN Basic information |
| Product Name: | PINOSYLVIN | | Synonyms: | (e)-5-stilbenediol;5-(2-phenylethenyl)-3-benzenedio(e)-;pinosylvine;AKOS 211-07;3,5-DIHYDROXY-STILBENE;3,5-TRANS-DIHYDROXYSTILBENE;5-(2-Phenylethenyl)benzene-1,3-diol;5-[(E)-2-Phenylethenyl]-1,3-benzenediol | | CAS: | 22139-77-1 | | MF: | C14H12O2 | | MW: | 212.24 | | EINECS: | 683-184-0 | | Product Categories: | Stilbenes (substituted) | | Mol File: | 22139-77-1.mol |  |
| | PINOSYLVIN Chemical Properties |
| Melting point | 153-157 °C | | Boiling point | 312.08°C (rough estimate) | | density | 1.1035 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | solubility | DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:50): 0.01mg/mL; DMSO: 10mg/mL; Ethanol: 20mg/mL; Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL | | form | A solid | | pka | 9.34±0.10(Predicted) | | BRN | 1870942 | | InChIKey | YCVPRTHEGLPYPB-VOTSOKGWSA-N | | LogP | 3.680 (est) |
| Hazard Codes | Xn,N | | Risk Statements | 22-36-51/53 | | Safety Statements | 26-61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | RTECS | WJ5580000 |
| | PINOSYLVIN Usage And Synthesis |
| Chemical Properties | Off-white crystalline powder | | Uses | Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility. | | Definition | ChEBI: Pinosylvin is a stilbenol. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | | Enzyme inhibitor | This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase. |
| | PINOSYLVIN Preparation Products And Raw materials |
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