4-(Dimethylamino)cinnamaldehyde

4-(Dimethylamino)cinnamaldehyde Basic information
Product Name:4-(Dimethylamino)cinnamaldehyde
Synonyms:4-DIMETHYLAMINOCINNAMALDEHYDE;4-(DIMETHYLAMINO)-CINNAMALDEHYDE REAGENT;4-(N,N-DIMETHYLAMINO)CINNAMALDEHYDE;4-Dimethylaminociamaldehyde;3-[4-(Dimethylamino)phenyl]prop-2-enal, N,N-Dimethyl-4-(3-oxoprop-1-en-1-yl)aniline;4-DiMethylaMinocinnaMaldehyde, 98% 25GR;4-DiMethylaMinocinnaMaldehyde, 98% 5GR;3-[4-(Dimethylamino)phenyl]acrylaldehyde 3-[4-(Dimethylamino)phenyl]-2-propenal
CAS:6203-18-5
MF:C11H13NO
MW:175.23
EINECS:228-267-0
Product Categories:A to Z;Building Blocks;C10-C12;Carbonyl Compounds;Chemical Synthesis;Core Bioreagents;D;Dyes;Hematology and Histology;Organic Building Blocks;Research Essentials;Stains &;Stains and Dyes;Pharmaceutical intermediate;Cinnamic acid;Absolute Configuration Determination (Exciton Chirality CD Method);Analytical Chemistry;Enantiomer Excess & Absolute Configuration Determination;Exciton Chirality CD Method (for Primary Amino Groups);Aromatic Aldehydes & Derivatives (substituted);DResearch Essentials;Core Bioreagents;Stains and Dyes;Stains&Dyes, A to;Aldehydes;C10 to C21;Carbonyl Compounds
Mol File:6203-18-5.mol
4-(Dimethylamino)cinnamaldehyde Structure
4-(Dimethylamino)cinnamaldehyde Chemical Properties
Melting point 138-140 °C(lit.)
Boiling point 306.53°C (rough estimate)
density 1.0582 (rough estimate)
refractive index 1.5260 (estimate)
storage temp. -20°C
solubility dioxane: 50 mg/mL, clear
form Powder
pka4.59±0.24(Predicted)
color Yellow to orange
Sensitive Air & Light Sensitive
BRN 972369
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKeyRUKJCCIJLIMGEP-ONEGZZNKSA-N
LogP2.630 (est)
CAS DataBase Reference6203-18-5(CAS DataBase Reference)
NIST Chemistry Reference2-Propenal, 3-[4-(dimethylamino)phenyl]-(6203-18-5)
EPA Substance Registry System2-Propenal, 3-[4-(dimethylamino)phenyl]- (6203-18-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR UN 1789 8/PG 3
WGK Germany 3
8-10-23
TSCA Yes
HS Code 29124990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
4-(Dimethylamino)cinnamaldehyde Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesUsed to determine the ability of an organism to split indole from the tryptophan molecule.
Uses4-(Dimethylamino)cinnamaldehyde is a reagent used in the assay of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
Uses4-(Dimethylamino)cinnamaldehyde is a reagent for assay of indole product of apotryptophanase and tryptophanase. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
DefinitionChEBI: 4-dimethylaminocinnamaldehyde is a member of cinnamaldehydes.
General DescriptionDMACA is basically a selective staining reagent. It helps identify the flavanols by staining them blue in color.
Biochem/physiol ActionsReagent for assay of indole product of apotryptophanase and tryptophanase. DMAC produces colored adducts with flavanols for subsequent HPLC. It has been used in a chromogenic method for quantifying proanthocyandines in cranberry powder.
Purification MethodsThe aldehyde crystallises from EtOH or ligroin and is dried in vacuo. The oxime has m 157o (from ligroin). The phenylhydrazone has m 169o (form MeOH). It is used as a reagent for amines (with NH3, UV has max at 630nm). [K.nig et al. Chem Ber 61 2075 2075, Quareshi & Kahn Anal Chim Acta 86 309 1976, Beilstein 14 III 184, 14 IV 197.]
4-(Dimethylamino)cinnamaldehyde Preparation Products And Raw materials
RARECHEM AK ML 0365 Cassia Aurantium P.E Catechins 8% HPLC 4-(Dimethylamino)cinnamaldehyde 2-PROPENAL, 3-(4-METHYLPHENYL)-,(2E) 4-(N,N-DIETHYLAMINO)CINNAMIC ACID alpha-Hexylcinnamaldehyde 3-[2-CHLORO-4-(DIMETHYLAMINO)PHENYL]-1-(4-CHLOROPHENYL)-2-PROPEN-1-ONE 3-[4-(DIMETHYLAMINO)PHENYL]-1-(4-METHOXYPHENYL)PROP-2-EN-1-ONE 1,5-BIS(4-DIMETHYLAMINOPHENYL)-1,4-PENTADIEN-3-ONE 3,3'-CARBONYLBIS(7-DIETHYLAMINOCOUMARIN) 3-(trifluoromethyl) Cinnamaldehyde 4-Dimethylaminobenzoic acid 3-[4-(DIMETHYLAMINO)PHENYL]-1-(2-THIENYL)PROP-2-EN-1-ONE 4-(DIMETHYLAMINO)-4'-FLUOROCHALCONE DI METHYL AMINO CINNAMALDEHYDE 4-(Dimethylamino)cinnamic acid Coumarin 338 α-Bromocinnamaldehyde

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