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| | 5-Methyl-2'-deoxycytidine Basic information |
| | 5-Methyl-2'-deoxycytidine Chemical Properties |
| Melting point | 217-219 °C(lit.) | | Boiling point | 492.8±55.0 °C(Predicted) | | density | 1?+-.0.1 g/cm3(Predicted) | | refractive index | 44 ° (C=1.4, H2O) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly) | | pka | pK1:4.33 (25°C) | | form | Powder | | color | White to Off-white | | Water Solubility | Soluble in water. | | Stability: | Hygroscopic | | CAS DataBase Reference | 838-07-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-24/25 | | WGK Germany | 3 | | RTECS | HA3860000 | | HS Code | 29389090 |
| | 5-Methyl-2'-deoxycytidine Usage And Synthesis |
| Description | 5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules. | | Chemical Properties | White Solid | | Uses | 5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation. It has been used in epigenetics research to investigate the dynamics of DNA methylation pattern in the control of gene expression. | | Uses | 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. | | Uses | A Cytidine (C998300) analog and also an isostere of Thymidine (T412000). | | Definition | ChEBI: 5-methyl-2'-deoxycytidine is a 2'-deoxycytidine. |
| | 5-Methyl-2'-deoxycytidine Preparation Products And Raw materials |
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