AURAMINE O

AURAMINE O Basic information
Product Name:AURAMINE O
Synonyms:PYOCTANINUM AUREUM;PYOCTANUNUM AUREUM;PYOKTANIN YELLOW;PYKOTANNIN;AURAMINE O, CERTIFIED;AURAMINE O, CERTIFIED (C.I. 41000);AURAMINE O, FOR MICROSCOPY;BASIC YELLOW 2
CAS:2465-27-2
MF:C17H22ClN3
MW:303.83
EINECS:219-567-2
Product Categories:Organics;Dyes and Pigments;Diphenylmethane
Mol File:2465-27-2.mol
AURAMINE O Structure
AURAMINE O Chemical Properties
Melting point >250 °C (dec.)(lit.)
storage temp. Inert atmosphere,Room Temperature
solubility 10g/l
Colour Index 41000
form Powder/Solid
pka9.8, 10.7(at 25℃)
color Yellow to ochre-yellow
PH6-7 (10g/l, H2O, 20℃)
PH Range6.5
Water Solubility Soluble in water or ethanol
λmax370 nm, 432 nm
BRN 4030061
Stability:Stable. Incompatible with strong oxidizing agents.
Biological ApplicationsDetecting bacteria; treatment of cancers,cardiovascular disease,diabetesassociated pain,mechanical allodynia,metabolic syndrome,protozoan infections in fish; targeted drug delivery; as fungal inhibitors
CAS DataBase Reference2465-27-2(CAS DataBase Reference)
NIST Chemistry ReferenceAniline, 4,4'-(imidocarbonyl)bis-(n,n-dimethyl)-, hydrochloride(2465-27-2)
EPA Substance Registry SystemAuramine, monohydrochloride (2465-27-2)
Safety Information
Hazard Codes T,Xn
Risk Statements 22-24-40-20/21/22
Safety Statements 36/37-45-36-22
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS BY3675000
TSCA Yes
HS Code 3204 13 00
HazardClass 6.1
PackingGroup III
Hazardous Substances Data2465-27-2(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 1000 mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
AURAMINE O Usage And Synthesis
Chemical PropertiesAuramine is a yellow crystalline powder or flaky material.
Chemical Propertiesyellow powder
UsesCertified for use by fluorescence microscopy in Churukian's modification of Truant's fluorescent method for acid fast bacilli on paraffin sections.
UsesFluorescent stain for acid-resistant bacteria in sputum
DefinitionChEBI: A hydrochloride obtained by combining 4,4'-carbonimidoylbis(N,N-dimethylaniline) with one molar equivalent of hydrogen chloride. A fluorescent stain for demonstrating acid fast organisms in a method similar to the Zieh Neelsen. It also can be used to make a fluorescent Schiff reagent.
General DescriptionYellow flakes or powder.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileAURAMINE O is incompatible with strong oxidizing agents.
HazardProbable carcinogen.
Fire HazardFlash point data for AURAMINE O are not available. AURAMINE O is probably combustible.
Potential ExposureAuramine is used industrially as a dye or dye intermediate for coloring textiles; paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery, and treatment of gonorrhea) and fungicide. Human exposure to auramine occurs principally through skin absorption or inhalation of vapors. Low-level dermal exposure to the consumer may occur but would be limited to any migration of auramine from fabric, leather, or paper goods.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Properties and Applications

TEST ITEMS

SPECIFICATION

APPEARANCE

DARK YELLOWPOWDER

SHADE

BRIGHT YELLOWISH

HEAT RESISTANCE

280 °C min

DENSITY

1.07 g/cm 3

WATER FASTNESS

4-5

LIGHT FASTNESS

1-2

BLEACHABILITY (OXIDATIVE)

4

BLEACHABILITY (REDUCTIVE)

3

WATER SOLUBILITY AT 20 °C

10 g/L min

WATER INSOLUBLE

1.0% max

MOISTURE

3.0% max

TINTING STRENGTH

100-105 %

WEIGHT METAL TOTAL

50ppm max

Purification MethodsIt crystallises from EtOH as the hydrochloride and is very slightly soluble in CHCl3, UV: 434nm ( 370). The free base (carbinolamine) has m 136o (from *C6H6). [Goldacre & Phillips J Chem Soc 1724 1949, Conrad et al. Biochemistry 9 1540 1970, Beilstein 14 IV 256.]
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incinerate in furnace with afterburner and scrubber.
AURAMINE O Preparation Products And Raw materials
Raw materialsN,N-Dimethylaniline-->Sulfanilic acid-->Benzhydrylamine-->N1,N1-DIETHYL-4-[4-(DIETHYLAMINO)BENZYL]ANILINE
4,4'-METHYLENEBIS(N-METHYLANILINE) Auramine/Rhodamine/Phenol Auramine Permanganate 0.1% Aqueous Auramine,monohydrate DUPONT AURAMINE SP Auramine Phenol Auramine Base,AURAMINE(TECHNICAL-GRADE) Auramine/Phenol 10x conc. Auramine Decolouriser (Lempert) DUPONT AURAMINE AURAMINE OS EX AURAMINE BASE (C.I. 41000:1) CALCOZINE AURAMINE OO AURAMINE DS-2203 CARBOLATED AURAMINE, SOLUTION ACCORDING TO DEGOMMIER,PHENOLIC AURAMINE SOLUTION,AURAMINE PHENOL (LEMPERT) AURAMINE BASE NS N-METHYL-4,4'-METHYLENEDIANILINE Auramine Fluorochrome Kit, Mycobacteria Fluorescent Stain Kit

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.