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| | L-HOMOCYSTEINE Basic information |
| Product Name: | L-HOMOCYSTEINE | | Synonyms: | BUTANOIC ACID, 2-AMINO-4-MERCAPTO-, (S)-;BUTYRIC ACID, 2-AMINO-4-MERCAPTO-, L-;L-HOMOCYSTEINE;(S)-HOMOCYSTEINE;(S)-2-AMINO-4-MERCAPTOBUTANOIC ACID;H-Hcys-OH;(S)-2-Amino-4-(methylmercapto)butanoic acid;Butyric acid, 2-amino-4-(methylthio)-, L- | | CAS: | 6027-13-0 | | MF: | C4H9NO2S | | MW: | 135.18 | | EINECS: | 227-891-0 | | Product Categories: | Amino Acids | | Mol File: | 6027-13-0.mol |  |
| | L-HOMOCYSTEINE Chemical Properties |
| Melting point | 232°C | | Boiling point | 299.7±35.0 °C(Predicted) | | density | 1.149 (estimate) | | refractive index | 1.5480 (estimate) | | storage temp. | -20°C | | solubility | Aqueous Acid (Sparingly, Heated, Sonicated), Water (Slightly, Heated) | | form | solid | | pka | 2.24±0.10(Predicted) | | color | White to Off-White | | optical activity | [α]/D 25.5±1.5°, c = 1 in 1 M HCl | | Stability: | Air Sensitive, Hygroscopic | | InChIKey | FFFHZYDWPBMWHY-VKHMYHEASA-N | | CAS DataBase Reference | 6027-13-0(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 29309090 | | Toxicity | mouse,LD50,intraperitoneal,> 1082mg/kg (1082mg/kg),Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1419, 1974. |
| | L-HOMOCYSTEINE Usage And Synthesis |
| Chemical Properties | Colourless or nearly colourless solid | | Uses | L-Homocysteine is the hydrolysis product of adenosine (A280400), a purine nucleoside. Metabolic fate of L-Homocysteine is converted back to L-Methionine( M260440) via tetrahydrofolate. | | Uses | L-homocysteine has been used as a supplement in cell culture media. | | Definition | ChEBI: Homocysteine with L configuration. | | General Description | L-homocysteine is used to diagnose homocystinuria. | | Biochem/physiol Actions | Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism. | | Purification Methods | Crystallise L-homocysteine from aqueous EtOH. All operations should be carried out under N2 as the thiol readily oxidizes in air. The acid (3g) is dissolved in freshly boiled H2O ( |
| | L-HOMOCYSTEINE Preparation Products And Raw materials |
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