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| | methyl L-tryptophanate Basic information |
| Product Name: | methyl L-tryptophanate | | Synonyms: | methyl L-tryptophanate;(2S)-2-Amino-3-(1H-indole-3-yl)propanoic acid methyl ester;(2S)-2-Amino-3-(1H-indole-3-yl)propionic acid methyl ester;(αS)-α-Amino-1H-indole-3-propanoic acid methyl ester;3-(1H-Indole-3-yl)-L-alanine methyl ester;(S)-Tryptophan methyl ester;(S)-METHYL 2-AMINO-3-(1H-INDOL-3-YL)PROPANOATE;Tryptophan methyl ester hydrochloride | | CAS: | 4299-70-1 | | MF: | C12H14N2O2 | | MW: | 218.25 | | EINECS: | 224-309-7 | | Product Categories: | | | Mol File: | 4299-70-1.mol |  |
| | methyl L-tryptophanate Chemical Properties |
| | methyl L-tryptophanate Usage And Synthesis |
| Uses | L-Tryptophan Methyl Ester is the acidic-free form of L-Tryptophan Methyl Ester Hydrochloride (T895010), which is an amino acid derivative that may be used to prepare the corresponding amino acid amide L-Trytophanamide Hydrochloride. Also, it is an intermediate used in the synthesis of (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester (B200020), which is a Tadalafil (T004500) derivative and used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity. |
| | methyl L-tryptophanate Preparation Products And Raw materials |
| Raw materials | L-Tryptophan, N,1-bis[(1,1-dimethylethoxy)carbonyl]-, methyl ester-->L-tryptophan monohydrochloride-->Tryptophan, N-benzoyl-, methyl ester (7CI)-->Methanol-->L-Tryptophan-->N-[(tert-Butoxy)carbonyl]-L-tryptophan | | Preparation Products | (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester-->H-PHE-TRP-OH-->cis-Tadalafil-->PHENYLTHIOHYDANTOIN TRYPTOPHAN)-->(2S)-2-amino-3-(1H-indol-3-yl)-N-methylpropanamide |
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