Lithium tri-tert-butoxyaluminum hydride

Lithium tri-tert-butoxyaluminum hydride Basic information

Product Name:	Lithium tri-tert-butoxyaluminum hydride
Synonyms:	Lithium hydridotris(tert-butoxy)aluminate, nominally 1M in THF, packaged under Argon in resealable ChemSealTM bottle;Lithium hydridotris(tert-butoxy)aluminate, 90% min;LITHIUM TRI-(T-BUTOXY)-ALUMINUM HYDRIDE;LITHIUM TRI-TERT-BUTOXYALUMINUM HYDRIDE;LITHIUM ALUMINIUM TRI-TERT-BUTOXYHYDRIDE;LITHIUM HYDRIDOTRIS(TERT-BUTOXY)ALUMINATE;LITHIUM HYDRIDOTRI-TERT-BUTOXOALUMINATE;LITHIUM TRI-TERT-BUTOXYALUMINOHYDRIDE, 1 .0M SOLUTION IN TETRAHYDROFURAN
CAS:	17476-04-9
MF:	C12H28AlO3.Li
MW:	254.27
EINECS:	241-490-8
Product Categories:	metal alkyl;Aluminum Hydrides;Synthetic Reagents;Al (Alminum) Compounds;Classes of Metal Compounds;Li (Lithium) Compounds;Reduction;Synthetic Organic Chemistry;Typical Metal Compounds;17476-04-9
Mol File:	17476-04-9.mol

Lithium tri-tert-butoxyaluminum hydride Chemical Properties

Melting point	300-319 °C (dec.) (lit.)
Boiling point	66°C (THF)
density	0.942 g/mL at 25 °C
Fp	95 °F
storage temp.	2-8°C
solubility	It is soluble in organic solvents at low temperatures.
form	Solution
color	Clear to slightly turbid colorless
Water Solubility	Reacts with water.
Sensitive	Air & Moisture Sensitive
BRN	5796791
Exposure limits	ACGIH: TWA 50 ppm; STEL 100 ppm (Skin) OSHA: TWA 200 ppm(590 mg/m3) NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
Stability:	Stable. Incompatible with alcohols. Reacts violently with water. Highly flammable.
InChIKey	BYBIDFZFKATBFH-UHFFFAOYSA-N
CAS DataBase Reference	17476-04-9(CAS DataBase Reference)
EPA Substance Registry System	Aluminate(1-), hydrotris(2-methyl-2-propanolato)-, lithium, (T-4)- (17476-04-9)

Safety Information

MSDS Information

Lithium tri-tert-butoxyaluminum hydride Usage And Synthesis

Chemical Properties	Lithium tri-tert-butoxyaluminum hydride is a white powder with a melting point of 319°C, which is sublimated under vacuum at 280°C. It is soluble in ethylene glycol dimethyl ether, diglyme and tetrahydrofuran, and slightly soluble in ether. Stable in dry air, hydrolyzed slowly in moist air. Lithium tri-tert-butoxyaluminum hydride is a mild and highly selective reducing agent. Ketones, aldehydes and acid chlorides can be reduced in diethyl ether or diglyme at 0°C, fatty acid esters and nitriles are not reduced, but phenyl esters of fatty acids and alicyclic acids can be reduced.
Uses	antimicrobial, cholesterol lowering agent, for ion-permeable synthetic membranes
Uses	Lithium tri-tert-butoxyaluminum hydride is less reactive than lithium aluminum hydride (LAH) and is very useful in selective reductions of acyl halides, aldehydes, ketones, and esters. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuff. LAH, is a reducing agent commonly employed in modern organic synthesis.
Preparation	Lithium aluminum hydride reacts with tert-butanol in ether to prepare Lithium tri-tert-butoxyaluminum hydride.
General Description	Lithium tri-tert-butoxyaluminum hydride is a mild reducing agent mainly used for the selective reduction of ketones.

Lithium tri-tert-butoxyaluminum hydride Preparation Products And Raw materials

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