Cefuroxime 1-acetoxyethyl ester

Cefuroxime 1-acetoxyethyl ester Basic information

Product Name:	Cefuroxime 1-acetoxyethyl ester
Synonyms:	1-(acetyloxy)ethylest;cxm-ax;(6R-(6alpha,7beta(Z)))-3-(((Aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester;Cefuroxime 1-acetoxyethyl ester;[6R-[6α，7β(Z)]]-3-[(Aminocarbonyloxy)methyl]-7-[2-(furan-2-y1)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-car-boxylic acid(2-acetoxy)ethylester;Elobact：Oraxim;Maxitil;(6R)-3-[[(Aminocarbonyl)oxy]methyl]-7α-[[2-furanyl[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-acetoxyethyl ester
CAS:	64544-07-6
MF:	C20H22N4O10S
MW:	510.47
EINECS:	638-760-6
Product Categories:	Pharmaceutical intermediates;Pharmaceutical intermediate;VIROPTIC;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;64544-07-6
Mol File:	64544-07-6.mol

Cefuroxime 1-acetoxyethyl ester Chemical Properties

Melting point	175-180 °C
Boiling point	250°C (rough estimate)
density	1.3927 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	-20°C
solubility	DMSO: soluble1mg/mL
pka	8.31±0.60(Predicted)
form	powder
color	white to off-white
InChIKey	KEJCWVGMRLCZQQ-UXXYIVIXSA-N
CAS DataBase Reference	64544-07-6(CAS DataBase Reference)

Safety Information

MSDS Information

Cefuroxime 1-acetoxyethyl ester Usage And Synthesis

Chemical Properties	White to Off-White Solid
Uses	Cefuroxime 1-acetoxyethyl ester is an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections.
Uses	It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial.
Uses	antiviral (opthalmic)
Definition	ChEBI: Cefuroxime axetil is a cephalosporin.

Cefuroxime 1-acetoxyethyl ester Preparation Products And Raw materials

Raw materials	Cefuroxime-->(E)-CefuroxiMe Axetil DISCONTINUED-->1-Bromoethyl acetate
Preparation Products	Diisopropyl ether

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