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| | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Basic information |
| Product Name: | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE | | Synonyms: | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE;TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE;TRANS-HEXAHYDROPHTHALIC ANHYDRIDE;1,3-Isobenzofurandione, hexahydro-, trans-;trans-cyclohexane-1,2-dicarboxylic anhydride;Einecs 238-009-9;cis-1.2-Cyclohexane dicarboxylic anhydride 1g [14166-21-3];trans-1,2-Cyclohexanedicarboxylic anhydride,trans-Hexahydrophthalic anhydride | | CAS: | 14166-21-3 | | MF: | C8H10O3 | | MW: | 154.16 | | EINECS: | 238-009-9 | | Product Categories: | | | Mol File: | 14166-21-3.mol |  |
| | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Chemical Properties |
| Melting point | 145-147 °C(lit.) | | Boiling point | 283.4±0.0 °C(Predicted) | | density | 1.235±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Acetone (Sparingly), Chloroform (Slightly), DMSO (Slightly) | | form | Solid | | color | White to Pale Beige | | Stability: | Moisture Sensitive | | CAS DataBase Reference | 14166-21-3 |
| | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Usage And Synthesis |
| Uses | Trans-1,2-cyclohexanedicarboxylic anhydride can be used as a reagent to prepare hepatitis C virus (HCV) and granzyme B (indoline derivatives) inhibitors. It has also been employed in studies relating to the development of protein kinase C inhibitors. | | Purification Methods | Crystallise the anhydride from *C6H6/Et2O. It has been obtained by heating the cis-acid or anhydride with HCl at 180o for 3hours. It can be obtained from the acid by heating in Ac2O. It sublimes at 125-135o/0.02mm. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Fichter & Simon Helv Chim Acta 17 1218 1934, Beilstein 9 IV 2802.] |
| | (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Preparation Products And Raw materials |
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