Thiophene-3-ethanol

Thiophene-3-ethanol Basic information

Product Name:	Thiophene-3-ethanol
Synonyms:	2-(3-Thienyl)ethanol, 3-(2-Hydroxyethy;3-(2-Hydroxyethyl)thiophene 98%;2-(thiophen-3-yl)ethanol;2-(3-Thienyl)ethanol, 3-(2-Hydroxyethyl)thiophene;2-(Thiophene-3-yl)ethanol;2-(3-Thienyl)ethanol,99%;2-(3-Thienyl)ethanol ,98%;2-(Thien-3-yl)ethan-1-ol
CAS:	13781-67-4
MF:	C6H8OS
MW:	128.19
EINECS:	237-434-7
Product Categories:	Thiophen;Functional Materials;Heterocycles;Thiophens;Reagents for Conducting Polymer Research;Thiophene Derivatives (for Conduting Polymer Research);1
Mol File:	13781-67-4.mol

Thiophene-3-ethanol Chemical Properties

Boiling point	110-111 °C14 mm Hg(lit.)
density	1.144 g/mL at 25 °C(lit.)
refractive index	n20/D 1.552(lit.)
Fp	199 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	14.92±0.10(Predicted)
form	Liquid
color	Clear colorless to yellow-brown
Specific Gravity	1.144
Water Solubility	Sparingly soluble in water(0.059 g/L at 25°C).
BRN	107080
InChIKey	YYPNNBPPDFTQFX-UHFFFAOYSA-N
LogP	1.07
CAS DataBase Reference	13781-67-4(CAS DataBase Reference)
NIST Chemistry Reference	3-Thiopheneethanol(13781-67-4)

Safety Information

Safety Statements	23-24/25
WGK Germany	3
F	10
HS Code	29349990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Thiophene-3-ethanol Usage And Synthesis

Chemical Properties	Clear colorless to yellowish-brown liquid
Uses	3-Thiopheneethanol is used as a reagent in the synthesis of pH-responsive near-IR emitting conjugated polymer nanoparticles for cellular imaging and controlled-drug delivery. 3-Thiopheneethanol is also used as a reagent in the preparation of potent respiratory syncytial virus RNA polymerase inhibitors.
Uses	3-Thiopheneethanol [3-(2-hydroxyethyl)thiophene] was used in the synthesis of various ether and ester derivatives such as 3-(2-(benzyloxy)ethyl)thiophene, 3-[2-((triphenylmethyl)oxy)ethyl]thiophene, 3-[2-((trimethylsilyl)oxy)ethyl]thiophene, 3-[2-((dimethyl-tert-butylsilyl)oxy)ethyl]thiophene, 3-(2-acetoxyethyl)thiophene and 3-(2-(benzoyloxy)ethyl)thiophene.

Thiophene-3-ethanol Preparation Products And Raw materials

Raw materials	Tetrahydrofuran-->n-Butyllithium-->Lithium Aluminum Hydride-->Nitrogen-->Methyl chloroacetate-->3-Bromothiophene
Preparation Products	2-(thiophen-3-yl)ethyl 4-methylbenzenesulfonate-->3-Thiopheneacetaldehyde

Thienyl 3-Thiophenemalonic acid Thiophene-3-ethanol Thianaphthene 5-CHLOROBENZO[B]THIOPHENE-3-ACETIC ACID Ethanol 2-Thenaldehyde D-(-)-3-thienylglycine (2-METHYL-THIOPHEN-3-YL)-ACETIC ACID Thiophene POLYTHIOPHENE Ethyl 2-(1-benzothiophen-3-yl)acetate 2-(2-THIENYL) ETHANOL (THIOPHENE-2-ETHANOL),THIOPHENE-2-ETHANOL 2-(METHYLSULFONYL)ETHANOL Ethyl acetate Thifensulfuron methyl Tetrahydrothiophene Cephalothin sodium

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