ChemicalBook Product Catalog Chemical Reagents Organic reagents Boric acid 2-Chloro-4-pyridylboronic acid

2-Chloro-4-pyridylboronic acid

2-Chloro-4-pyridylboronic acid Basic information
Product Name:2-Chloro-4-pyridylboronic acid
Synonyms:Boronic acid, (2-chloro-4-pyridinyl)- (9CI);2-CHLORO-4-PYRIDINEBORONIC ACID;2-CHLORO-4-PYRIDINYLBORONIC ACID;2-CHLORO-4-PYRIDYLBORONIC ACID;AKOS BRN-0495;2-Chloropyridine-4-Boronic;Boronic acid, B-(2-chloro-4-pyridinyl)-;B-(2-Chloro-4-pyridinyl)-boronic acid
CAS:458532-96-2
MF:C5H5BClNO2
MW:157.36
EINECS:628-060-9
Product Categories:Boric acid series;Boronate Ester;Potassium Trifluoroborate;Boronic Acids;Boronic Acids and Derivatives;Heteroaryl;Boronic acids;Boronic acid;Organoborons;Pyridine;BORONICACID;blocks;BoronicAcids;Pyridines
Mol File:458532-96-2.mol
2-Chloro-4-pyridylboronic acid Structure
2-Chloro-4-pyridylboronic acid Chemical Properties
Melting point 155-163 °C
Boiling point 355.2±52.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form powder to crystal
pka6.57±0.10(Predicted)
color White to Almost white
InChIKeyWJYRVVDXJMJLTN-UHFFFAOYSA-N
CAS DataBase Reference458532-96-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Chloro-4-pyridylboronic acid Usage And Synthesis
Chemical PropertiesWhite solid
Uses2-Chloropyridine-4-boronic Acid is a substrate in a peroxide mediated hydroxydeboronation providing good yields of halohydroxypyridines. It is also a reagent used to prepare IRAK-4 inhibitors.
General DescriptionMay contain varying amounts of anhydride
2-Chloro-4-pyridylboronic acid Preparation Products And Raw materials
Preparation Products2-Chloro-4-hydroxypyridine-->2,2'-DICHLORO-[4,4']-BIPYRIDINE-->2,2'-DICHLORO-[3,4']-BIPYRIDINE
2,5-DICHLORO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE 2-CHLORO-6-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-CHLORO-5-FLUOROPYRIDINE-4-BORONIC ACID 2-Chloro-4-bromopyridine 2-CHLORO-3-FLUOROPYRIDINE-4-BORONIC ACID 2-Trifluoromethyl-6-chloro-5-pyridineboric acid MCPA SOLUTION 100 NG/MYL IN ACETONITRIL& pyridinium Chlorochromate 2-CHLORO-5-PYRIDYLBORONIC ACID PINACOL ESTER 4-CHLORO3-PYRIDYLBORONIC ACID 2-CHLORO-3-FLUORO-5-PICOLINE-4-BORONIC ACID 2-CHLORO-3-FLUOROPYRIDINE-4-BORONIC ACID HYDRATE 2,3-DICHLORO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE MCPA SODIUM 3-Chloro-4-pyridineboronic acid hydrate 2-CHLORO-3-FORMYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 3-Pyridylboronic acid 5-BROMO-2-CHLORO-4-PYRIDINEBORONIC ACID
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