6-Methylpyridazin-3(2H)-one

6-Methylpyridazin-3(2H)-one Basic information
Product Name:6-Methylpyridazin-3(2H)-one
Synonyms:6-Methyl-2,3-dihydropyridazine-3-one;3-pyridazinol, 6-methyl-;3-methyl-1H-pyridazin-6-one;6-Methyl-2H-pyridazin-3-o...;3-Hydroxy-6-methylpyridazine;6-Methylpyridazine-3[2H]-one;6-Methyl-1,2-dihydropyriMidin-2-one;6-Methyl-3-pyridazinone
CAS:13327-27-0
MF:C5H6N2O
MW:110.11
EINECS:236-367-0
Product Categories:
Mol File:13327-27-0.mol
6-Methylpyridazin-3(2H)-one Structure
6-Methylpyridazin-3(2H)-one Chemical Properties
Melting point 143-145°C
density 1.22±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka11.51±0.40(Predicted)
color Light yellow to Amber to Dark green
BRN 109928
CAS DataBase Reference13327-27-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 22-24/25-37-26
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
ALFA English
6-Methylpyridazin-3(2H)-one Usage And Synthesis
Uses6-?Methyl-?3-?pyridazinone is a lignin-based dye used on wool. 6-?Methyl-?3-?pyridazinone is also used as a reactant for the synthesis of C-?(1-?aryl-?cyclohexyl)?-?methylamine derivatives as selective, orally available inhibitors of dipeptidyl peptidase IV, imidazopyridazinone derivatives as PDE7 inhibitors and pyridazinone derivatives with an arylpiperazinylalkyl chain as a potentent, orally active, antinociceptive agent.
DefinitionChEBI: 6-Methylpyridazin-3(2H)-one is a member of pyridazines.
Synthesis Reference(s)Synthesis, p. 1158, 1994 DOI: 10.1055/s-1994-25663
6-Methylpyridazin-3(2H)-one Preparation Products And Raw materials
Preparation Products3-bromo-6-methylpyridazine-->6-Chloro-pyridazine-3-carboxylic acid ethyl ester-->3-MERCAPTO-6-METHYLPYRIDAZINE
6-Methylpyridazin-3(2H)-one Sulfamethoxypyridazine 4-HYDROXY-1-(4-METHYLPHENYL)-6-OXO-1,6-DIHYDRO-3-PYRIDAZINECARBOXYLIC ACID 1-(2,4-DICHLOROPHENYL)-4-HYDROXY-6-OXO-1,6-DIHYDRO-3-PYRIDAZINECARBOXYLIC ACID Hydralazine 2-tert-Butyl-4,5-dichloro-3-2H-pyridazinone Pyridaphenthion METHYL 1-(2,4-DICHLOROPHENYL)-4-HYDROXY-6-OXO-1,6-DIHYDRO-3-PYRIDAZINECARBOXYLATE 5-ACETYL-4-AMINO-2,6-DIMETHYL-2,3-DIHYDROPYRIDAZIN-3-ONE 6-Oxo-1,6-dihydro-pyridazine-3-carboxylicacid 6-(2-THIENYL)-3(2H)-PYRIDAZINONE METHYL 4-HYDROXY-6-OXO-1-PHENYL-1,6-DIHYDRO-3-PYRIDAZINECARBOXYLATE Sulfachloropyridazine sodium 4-CHLORO-1-(2,4-DICHLOROPHENYL)-6-OXO-1,6-DIHYDRO-3-PYRIDAZINECARBONITRILE 3(2H)-Pyridazinone METHYL 4-HYDROXY-1-(4-METHYLPHENYL)-6-OXO-1,6-DIHYDRO-3-PYRIDAZINECARBOXYLATE SULFACHLOROPYRIDAZINE Thioridazine

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