ChemicalBook Product Catalog Chemical Reagents Organic reagents fatty acid 2-HYDROXYHEXADECANOIC ACID

2-HYDROXYHEXADECANOIC ACID

2-HYDROXYHEXADECANOIC ACID Basic information
Product Name:2-HYDROXYHEXADECANOIC ACID
Synonyms:HYDROXYPALMITIC ACID, 2-;DL-ALPHA-HYDROXYPALMITIC ACID;2-HYDROXYPALMITIC ACID;(+/-)-2-HYDROXYHEXADECANOIC ACID;2-HYDROXYHEXADECANOIC ACID;2-HYDROXY C16:0 ACID;alpha-Hydroxypalmitic acid;Hexadecanoic acid, 2-hydroxy-
CAS:764-67-0
MF:C16H32O3
MW:272.42
EINECS:212-129-1
Product Categories:Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives
Mol File:764-67-0.mol
2-HYDROXYHEXADECANOIC ACID Structure
2-HYDROXYHEXADECANOIC ACID Chemical Properties
Melting point 86 °C
Boiling point 405.5±18.0 °C(Predicted)
density 0.955±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility very faint turbidity in Methanol
form powder to crystal
pka3.86±0.21(Predicted)
color White to Almost white
LogP6.210 (est)
CAS DataBase Reference764-67-0(CAS DataBase Reference)
Safety Information
WGK Germany 3
HS Code 2918.19.9000
MSDS Information
ProviderLanguage
SigmaAldrich English
2-HYDROXYHEXADECANOIC ACID Usage And Synthesis
Uses2-Hydroxyhexadecanoic Acid is used in the investigation of role of hypoxia in mechanism of action of elisidepsin which reduces drug efficiency by inhibiting hydroxylation and altering structure of lipid rafts in human SKBR-3, MCF-7, MDA-MB-453 cell lines. Also used in the studies on the antiviral activity of hydroxy fatty acids.
DefinitionChEBI: A 2-hydroxy fatty acid comprising a C16 straight chain carrying a hydroxy substituent at position 2.
Biochem/physiol Actions2-Hydroxyhexadecanoic acid (2OH-HDA) is used as a representative of the saturated long-chain hydroxyl fatty acids group, members of which have potential roles in anti-inflammatory action, neuroprotection, and bactericide and anti-cancer defense.
2-HYDROXYHEXADECANOIC ACID Preparation Products And Raw materials
Raw materialsHexadecanoic acid, 2-iodo--->2-HEXADECENOIC ACID-->2-BROMOHEXADECANOIC ACID-->Ethanol
16-Hydroxyhexadecanoic acid 2,2-bis(hydroxymethyl)butyl ester 2(R,S)-Hydroperoxyhexadecanoic?Acid? [S,(-)]-2-Hydroxyhexadecanoic acid sodium salt 12-Hydroxyhexadecanoic acid 11-Oxahexadecan-16-olide 8-Hydroxyhexadecanoic acid methyl ester 13-Hydroxyhexadecanoic acid methyl ester 7(R)-HYDROXYHEXADECANOIC ACID 2-HYDROXYHEXADECANOIC ACID METHYL ESTER (±)-threo-9,10-Dihydroxyhexadecanoic?acid? 9-Hydroxyhexadecanoic acid 3-HYDROXYHEXADECANOIC ACID METHYL ESTER Bis(16-hydroxyhexadecanoic acid)2-ethyl-2-(hydroxymethyl)-1,3-propanediyl ester (+/-)-3-HYDROXYHEXADECANOIC ACID,3-HYDROXYHEXADECANOIC ACID 5-Hydroxyhexadecanoic acid (+/-)-2-HYDROXYHEXADECANOIC ACID,2-HYDROXYHEXADECANOIC ACID 11-Hydroxyhexadecanoic acid 9,10,16-Trihydroxyhexadecanoic?acid?(Aleuritic)?Methyl?ester
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