ERYTHROSIN B

ERYTHROSIN B Basic information
Product Name:ERYTHROSIN B
Synonyms:ERYTHROSIN B;ERYTHROSIN BLUISH;ERYTHROSIN B, POLYMER BOUND;ERYTHROSIN, DISODIUM SALT;ERYTHROSINE;ERYTHROSINE B;ERYTHROSINE B STAIN;ERYTHROSIN EXTRA BLUISH
CAS:16423-68-0
MF:C20H9I4NaO5
MW:859.89
EINECS:240-474-8
Product Categories:Organics;Analytical Chemistry;Food Colors by Food Sanitation Law in Japan;PENETREX;Fluorescent;Xanthene
Mol File:16423-68-0.mol
ERYTHROSIN B Structure
ERYTHROSIN B Chemical Properties
Melting point 142~144℃
density 0.98
vapor pressure 0Pa at 25℃
Fp 285℃
storage temp. room temp
solubility 100g/l
Colour Index 45430
pka4.1(at 25℃)
form Fine Powder
color Deep red to brown
PH6-7 (10g/l, H2O, 20℃)
PH Range0(yellow)-3.6(red)
Water Solubility Soluble in water
λmax525nm
Merck 14,3693
BRN 1443945
Stability:Stable. Incompatible with strong oxidizing agents.
Biological ApplicationsDetecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity
Major Applicationcolor filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy
InChIKeyRAGZEDHHTPQLAI-UHFFFAOYSA-L
LogP-1.163 at 25℃
CAS DataBase Reference16423-68-0
EPA Substance Registry SystemErythrosine B (16423-68-0)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
WGK Germany 3
RTECS LM5950000
HS Code 32129000
Hazardous Substances Data16423-68-0(Hazardous Substances Data)
ToxicityLD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
ERYTHROSIN B Usage And Synthesis
DescriptionFD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .

Chemical Propertiesred to brown powder
Usesantibacterial
UsesErythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.
UsesBiological stain; color additive.
UsesErythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.
Preparationfluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt.
DefinitionChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.
General DescriptionErythrosin B (C.I. 45430)for microscopy Certistain?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Flammability and ExplosibilityNotclassified
Biochem/physiol ActionsErythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.
storageRoom temperature
Properties and Applicationsblue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.
Standard Light Fastness Soaping Persperation Fastness Oxygen bleaching Fastness to seawater
Fading Stain Fading Stain Fading Stain
ISO 1 3 4 1 2-3
ERYTHROSIN B Fluorescein Sodium 4-HYDROXY-3-IODOBENZYL ALCOHOL 2-HYDROXY-5-IODOBENZYL ALCOHOL 5-IODO-2-METHOXYTOLUENE 2,4,5,7-Erythrosi 2-IODOBENZENE-1,3-DIOL ERYTHROSIN B - SOLUTION ROSE BENGAL 2,4-DIIODOPHENOL ERYTHROSIN AMINE 4-Iodoanisole 4-IODODIPHENYL ETHER ANTI-ERYTHROSIN 4-IODOPHENYL ETHER ERYTHROSIN,ERYTHROSIN B LACTONE,ERYTHROSIN B,ERYTHROSIN B, SPIRIT SOLUBLE 4-Iodophenol TETRAIODOPHENOLPHTHALEIN

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