TOLFENPYRAD

TOLFENPYRAD Basic information
Description References
Product Name:TOLFENPYRAD
Synonyms:omi-88;tolfenpyrad (bsi, pa iso);TOLFENPYRAD STANDARD;HATI-HATI;4-chloro-3-ethyl-1-Methyl-N-(4-(p-tolyloxy)benzyl)-1H-pyrazole-5-carboxaMide;1H-Pyrazole-5-carboxaMide, 4-chloro-3-ethyl-1-Methyl-N-[[4-(4-Methylphenoxy)phenyl]Methyl]-;TOLFENPYRAD;mmbc mab-c mmb-chminaca fubamb
CAS:129558-76-5
MF:C21H22ClN3O2
MW:383.87
EINECS:
Product Categories:Agro-Products;Amines;Aromatics;Heterocycles;Pharmaceutical intermediates
Mol File:129558-76-5.mol
TOLFENPYRAD Structure
TOLFENPYRAD Chemical Properties
Melting point 87~89℃
Boiling point 540.0±50.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility Chloroform (Slightly), DMSO (Slightly)
pka13.11±0.46(Predicted)
form neat
BRN 13666608
InChIKeyWPALTCMYPARVNV-UHFFFAOYSA-N
CAS DataBase Reference129558-76-5
EPA Substance Registry System1H-Pyrazole-5-carboxamide, 4-chloro-3-ethyl-1-methyl-N-[[4-(4-ethylphenoxy)phenyl]methyl]- (129558-76-5)
Safety Information
Hazard Codes Xn,N
Risk Statements 20/22-50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany 3
MSDS Information
TOLFENPYRAD Usage And Synthesis
DescriptionTolfenpyrad is a pyrazole insecticide developed by Mitsubishi Chemical. It was first approved in 2002 in Japan under the trade name of Hachi-hachi.
It has broad insecticidal activity against a variety of pests such as Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera and Acarina. It is especially effective against pests that are resistant to existing insecticides such as organophosphates and carbametes, because it supposedly possesses a new mode of action: inhibition of Complex I in the respiratory electron-transfer chain of mitochondria. It is applied for vegetables particularly cruciferous leafy varieties, cucurbits, cole crops, tea, fruits & nuts, selected row crops, and indoor ornamentals except cut flowers.
References[1] http://sitem.herts.ac.uk/aeru/iupac/Reports/1687.htm  
[2] Koji Yamaguchi,  Wakako Hikiji, Masahiko Takino, Kanju Saka, Makiko Hayashida, Tatsushige Fukunaga, Youkichi Ohno (2012) Analysis of Tolfenpyrad and its Metabolites in Plasma in a Tolfenpyrad Poisoning Case, 36, 529-537
UsesTolfenpyrad
DefinitionChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 4-chloro-3-ethyl-1-methylpyrazole-5-carboxylic acid with the amino group of 1-[4-(4-methylphenoxy)phenyl]methylamine.
TOLFENPYRAD Preparation Products And Raw materials
Chlorantraniliprole Metaldehyde Clomiphene Citrate Indoxacarb Pymetrozine Best price of 6-EAPB AZIDITHION Chlorfenapyr SILAFLUOFEN tert-Butanol bk-DMBDB (hydrochloride) mab-c mmb-chminaca fubamb N-ethyl-p-methoxy-alpha-methylphenethylamine Fipronil Oxazole Dinotefuran Metaldehyde TOLFENPYRAD

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