ChemicalBook Product Catalog Biochemical Engineering Inhibitors Neuronal Signaling GABA Receptor agonists (R)-Baclofen

(R)-Baclofen

(R)-Baclofen Basic information
Product Name:(R)-Baclofen
Synonyms:Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, (βR)-;D-Baclofen;l-Baclofen;4-azanyl-3-(4-chlorophenyl)butanoic acid;(R)-4-Amino-3-(4-chlorophenyl)butyric acid;(βR)-β-(AMinoMethyl)-4-chlorobenzenepropanoic Acid;STX 209;Benzenepropanoic acid, b-(aMinoMethyl)-4-chloro-, (bR)-
CAS:69308-37-8
MF:C10H12ClNO2
MW:213.66
EINECS:
Product Categories:Inhibitors;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;GABA/Glycine receptor
Mol File:69308-37-8.mol
(R)-Baclofen Structure
(R)-Baclofen Chemical Properties
Melting point 171-174°C
Boiling point 364.3±32.0 °C(Predicted)
density 1.285±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
Water Solubility Practically insoluble in water
solubility Methanol (Slightly, Sonicated), Water (Slightly, Sonicated)
pka4.04±0.10(Predicted)
form powder to crystaline
color White to Almost white
CAS DataBase Reference69308-37-8(CAS DataBase Reference)
Safety Information
RIDADR 2811
RTECS DA8339450
HS Code 2922.49.2600
HazardClass 6.1
PackingGroup III
MSDS Information
(R)-Baclofen Usage And Synthesis
Chemical PropertiesWhite Solid
Uses(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
UsesR-Enantiomer of Baclofen. Specific GABA-B receptor agonist. Muscle relaxant (skeletal).
DefinitionChEBI: Arbaclofen is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.
Biological ActivityMore active enantiomer of ( RS )-Baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid) , a selective GABA B agonist.
storageRoom temperature
(R)-Baclofen Preparation Products And Raw materials
2-amino-2-(4-chlorophenyl)butanoic acid (R)-Baclofen 4-(4-CHLOROPHENYL)PYRROLIDINE-3-METHYLCARBOXYLATE BACLOFEN (-), [BUTYL-4-3H(N)] (R)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID trans-1-Boc-4-(4-chlorophenyl)-3-pyrrolidinecarboxylic acid Trans (+/-) 4-(4-Chlorophenyl)Pyrrolidine-3-Methylcarboxylate Hydrochloride (2R,3S)-BETA-P-CHLOROPHENYLGLUTAMIC ACID R(+)-Baclofen.Hydrochloride 3-AMINO-4-(3-CHLOROPHENYL)BUTANOIC ACID (R)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE FMOC-(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID,N-(9-FLUORENYLMETHOXYCARBONYL)-(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID (R)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOIC ACID (R)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE (S)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOIC ACID,(S)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOIC ACID HYDROCHLORIDE N-T-BUTOXYCARBONYL-(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID,BOC-(S)-3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID 4-AMINO-3-[4-CHLOROPHENYL]BUTANOIC ACID,(RS)-4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID,(3RS)-4-AMINO-3-(P-CHLOROPHENYL)BUTANOIC ACID 3-AMINO-4-(4-CHLOROPHENYL)BUTANOIC ACID
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