(-)-Corey lactone 4-phenylbenzoate alcohol

(-)-Corey lactone 4-phenylbenzoate alcohol Basic information
Description
Product Name:(-)-Corey lactone 4-phenylbenzoate alcohol
Synonyms:(3AALPHA,4ALPHA,5BETA,6AALPHA)-(-)-HEXAHYDRO-4-(HYDROXYMETHYL)-2-OXO-2H-CYCLOPENTA[B]FURAN-5-YL 1,1'-BIPHENYL-4-CARBOXYLATE;(-)-COREY LACTONE 4-PHENYLBENZOATE;4-Phenylbenzoyl corey lactone;(-)-COREY LACTONE 4-PHENYLBENZOATE ALCOHOL 99%;(-)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL;(3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one, 99%;[1,1'-Biphenyl]-4-carboxylicacid,(3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-ylester;BPCOD
CAS:31752-99-5
MF:C21H20O5
MW:352.38
EINECS:608-667-5
Product Categories:Prostaglandins;Latanoprost;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:31752-99-5.mol
(-)-Corey lactone 4-phenylbenzoate alcohol Structure
(-)-Corey lactone 4-phenylbenzoate alcohol Chemical Properties
Melting point 131-132 °C(lit.)
alpha -89 º (c=1, CHCl3)
Boiling point 446°C (rough estimate)
density 1.1818 (rough estimate)
refractive index 1.5400 (estimate)
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate
pka14.79±0.10(Predicted)
form Solid
color Off-White to Pale Yellow
optical activity[α]20/D 87°, c = 1 in chloroform
Water Solubility insoluble
BRN 1294692
InChIKeySZJVIFMPKWMGSX-UHFFFAOYSA-N
CAS DataBase Reference31752-99-5(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
(-)-Corey lactone 4-phenylbenzoate alcohol Usage And Synthesis
Description(-)-Corey lactone 4-phenylbenzoate alcohol is one of the isomers of biphenyl-4-formylcorilactone, which can be used for the synthesis of prostaglandins. Prostaglandins are a class of important endogenous physiologically active substances, important mediators of various physiological processes, and have high pharmacological activity. Clinically, prostaglandins are all artificially synthesized.
Chemical PropertiesOff-White to Pale Yellow Solid
Uses(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF.
(-)-Corey lactone 4-phenylbenzoate alcohol Preparation Products And Raw materials
Preparation Products(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE-->(+)-Cloprostenol-->Latanoprost Lactone Diol-->[1,1'-Biphenyl]-4-carboxylic acid [3aR-[3aa,4a(E),5b,6aa]]-4-[4-(3-chlorophenoxy)-3-oxo-1-butenyl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester-->[1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-5-yl ester
7-ALPHA-HYDROXY-CIS-OXABICYCLO[3.3.0]OCTANE-3-ONE (-)-Corey lactone 4-phenylbenzoate alcohol (-)-Corey Lactone Benzoate (-)-Corey lactone diol 4-Biphenylcarboxylic acid (S)-4-HEPTANOLIDE STANDARD FOR GC gamma-Octanoic lactone 1,3-CYCLOPENTANEDIOL (+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL 3-BENZYLOXY-2-METHYL-1-PROPANOL RACEMIC COREY LACTONE P-PHENYLBENZOATE ALCOHOL 6-BENZYLOXY-HEXANAL BIPHENYL-3-CARBOXYLIC ACID ETHYL ESTER (2-METHYL-CYCLOPENTYL)-ACETIC ACID Corey lactone p-phenylbenzoate alcohol 4-Heptanolide Methyl 4-phenylbenzoate CYCLOPENTYLACETIC ACID

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