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| | 8-Aminooctanoic acid Basic information |
| Product Name: | 8-Aminooctanoic acid | | Synonyms: | H-AOC(8)-OH;8-AMINOOCTANOIC ACID;Octanoic acid, 8-amino-;w-Aminocaprylic acid;H-8-AMINOCAPRYLIC ACID;H-8-AMINOOCTANOIC ACID;GAMMA-AMINOCAPRYLIC ACID;NH2-(CH2)7-COOH | | CAS: | 1002-57-9 | | MF: | C8H17NO2 | | MW: | 159.23 | | EINECS: | 213-687-9 | | Product Categories: | Amino Acids | | Mol File: | 1002-57-9.mol |  |
| | 8-Aminooctanoic acid Chemical Properties |
| Melting point | 194 °C (dec.) (lit.) | | Boiling point | 286.0±23.0 °C(Predicted) | | density | 1.0500 (estimate) | | refractive index | 1.4630 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Methanol (Very Slightly), Water (Slightly) | | pka | 4.76±0.10(Predicted) | | form | Crystalline Powder | | color | White to slightly beige | | Water Solubility | Soluble in water. | | BRN | 1756493 | | InChI | InChI=1S/C8H17NO2/c9-7-5-3-1-2-4-6-8(10)11/h1-7,9H2,(H,10,11) | | InChIKey | UQXNEWQGGVUVQA-UHFFFAOYSA-N | | SMILES | C(O)(=O)CCCCCCCN | | CAS DataBase Reference | 1002-57-9(CAS DataBase Reference) | | NIST Chemistry Reference | 8-Aminocaprylic acid(1002-57-9) |
| | 8-Aminooctanoic acid Usage And Synthesis |
| Chemical Properties | WHITE TO SLIGHTLY BEIGE CRYSTALLINE POWDER | | Uses | 8-Aminooctanoic acid is involved in the preparation of lactams using enzyme catalyzed aminolysis. | | Definition | ChEBI: 8-aminooctanoic acid is an omega-amino fatty acid that is octanoic acid which carries an amino group at position 8. It has a role as a human metabolite. It is a medium-chain fatty acid and an omega-amino fatty acid. | | Synthesis | In a 1 l flask with paddle stirrer, internal thermometer and reflux condenser, 142.6 g (1 mol) of 2-azacyclononanone and 110 g (1 mol) of about 36 wt.-% sodium hydroxide solution are boiled under reflux for 4 hours. The solution is subsequently cooled to about 80 °C and mixed with Lewatit SP-112?. After one hour, the acidic ion exchanger is filtered. 500 g of 2-Propanol is added dropwise to the mixture at 80 °C, and the homogeneous solution is slowly cooled to -5 °C. The precipitated solid is filtered and washed with 50 g of 2-propanol. After drying at 85 °C and 20 mbar, 8-Aminooctanoic acid is obtained as a fine colorless powder. A colorless powder. Yield: 127 g (80%). Melting point: 191-193 °C (Lit.: 194 °C).
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| | 8-Aminooctanoic acid Preparation Products And Raw materials |
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