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| | Dideoxyadenosine Basic information |
| | Dideoxyadenosine Chemical Properties |
| Melting point | 181-184 °C(lit.) | | alpha | D25 -25.2° (c = 1.01 in water) | | Boiling point | 377.64°C (rough estimate) | | density | 1.2455 (rough estimate) | | refractive index | -34 ° (C=1, H2O) | | storage temp. | -20°C | | solubility | DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble | | pka | pKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain) | | form | Powder | | color | White to Off-white | | Water Solubility | 43.2g/L(25 ºC) | | Merck | 14,3101 | | BRN | 619924 | | InChIKey | WVXRAFOPTSTNLL-NKWVEPMBSA-N | | CAS DataBase Reference | 4097-22-7(CAS DataBase Reference) | | EPA Substance Registry System | Adenosine, 2',3'-dideoxy- (4097-22-7) |
| | Dideoxyadenosine Usage And Synthesis |
| Chemical Properties | Beige power | | Uses | A potent labelled anti-HIV agent. | | Uses | A potent anti-HIV agent. | | Uses | Dideoxy Adenosine (Didanosine EP Impurity G) is a potent anti-HIV agent. | | Uses | 2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation. | | Definition | ChEBI: A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine. | | General Description | Off-white powder. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | Dideoxyadenosine may be sensitive to prolonged exposure to light. | | Health Hazard | SYMPTOMS: Symptoms of exposure to a related compound include cutaneous eruptions, fever, mouth sores, thrombocytopenia, neutropenia, reversible peripheral neuropathy, gastrointestinal distress, headache, nausea and vomiting. | | Fire Hazard | Flash point data for Dideoxyadenosine are not available; however, Dideoxyadenosine is probably combustible. |
| | Dideoxyadenosine Preparation Products And Raw materials |
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