|
| | Sulfacetamide sodium Basic information |
| Product Name: | Sulfacetamide sodium | | Synonyms: | SULFACETAMIDE SODIUM MONOHYDRATE;SULFACETAMIDE SODIUM SALT HYDRATE;SODIUM SULFACETAMIDE HYDRATE;N-SULFANILYLACETAMIDE MONOSODIUM SALT, MONOHYDRATE;N1-ACETYLSULFANILAMIDE MONOSODIUM SALT MONOHYDRATE;N1-ACETYLSULFANILAMIDE SODIUM SALT HYDRATE;N-(4-AMINOPHENYL-SULFONYL)ACETAMIDE SODIUM SALT HYDRATE;BIO-FARMA BF003142 | | CAS: | 6209-17-2 | | MF: | C8H13N2NaO4S | | MW: | 256.25 | | EINECS: | 642-939-4 | | Product Categories: | ALBUCID | | Mol File: | 6209-17-2.mol |  |
| | Sulfacetamide sodium Chemical Properties |
| Melting point | 263-265°C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | H2O: soluble50mg/mL | | form | powder | | color | white to off-white | | Water Solubility | Freely soluble in water. Insoluble in chloroform, ether, and benzene. | | CAS DataBase Reference | 6209-17-2 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37 | | WGK Germany | 3 | | RTECS | AC8480000 | | HS Code | 29350090 |
| | Sulfacetamide sodium Usage And Synthesis |
| Chemical Properties | White or yellowish-white, crystalline powder. | | Uses | Antibacterial;Inhibitor of folic acid synthesis | | Uses | Sulfacetamide sodium salt hydrate is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections. It adapts to cure trachoma, conjunctivitis, keratitis. | | Definition | ChEBI: Sulfacetamide sodium is an organic sodium salt that is the monohydrate form of sulfacetamide sodium. It has a role as an antimicrobial agent, an antiinfective agent and an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. It is an organic sodium salt and a hydrate. It contains a member of sulfacetamide sodium anhydrous. | | General Description | N-Sulfanilylacetamide monosodium salt (Sodium Sulamyd)is obtained as the monohydrate and is a white, odorless, bitter,crystalline powder that is very soluble (1:2.5) in water.Because the sodium salt is highly soluble at the physiologicalpH of 7.4, it is especially suited, as a solution, forrepeated topical applications in the local management ofophthalmic infections susceptible to sulfonamide therapy. | | Biochem/physiol Actions | Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis. |
| | Sulfacetamide sodium Preparation Products And Raw materials |
|
