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| Product Name: | TAK875 | | Synonyms: | [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate;TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid;TAK-875(0.5H2O);(3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1);TAK875 hemihydrate;CS-1926;TAK-875 hymihydrate | | CAS: | 1374598-80-7 | | MF: | C58H66O15S2 | | MW: | 1067.26564 | | EINECS: | | | Product Categories: | API;Inhibitors | | Mol File: | 1374598-80-7.mol |  |
| | TAK875 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: 100 mg/mL (187.40 mM);Ethanol: Insoluble | | Water Solubility | Water: Insoluble | | InChIKey | OJXYMYYDAVXPIK-IWKNALKQSA-N | | CAS DataBase Reference | 1374598-80-7 |
| | TAK875 Usage And Synthesis |
| Characteristics | More potent at activating hGPR40 than oleic acid | | Biological Activity | TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid. | | target | | Target | Value | GPR40
(CHO cells expressing human GPR40) | < td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 14 nM(EC50)
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