2-Bromo-4-methylpyridine

2-Bromo-4-methylpyridine Basic information

Product Name:	2-Bromo-4-methylpyridine
Synonyms:	2--4- MethylpyridinebroMide;Pyridine,2-broMo-4-Methyl-;2-Bromo-4-methylpyridine,96%;RARECHEM AH CK 0041;2-BROMO-4-METHYLPYRIDINE 99%;2-Bromo-4-MythylPyridine;2-BROMO-4-MEFHYL PYRIDINE;2-BROMO-4-METHYLPYRIDINE
CAS:	4926-28-7
MF:	C6H6BrN
MW:	172.02
EINECS:	625-590-2
Product Categories:	alkyl bromide;Aromatics;Bromopyridines;Halopyridines;Boronic Acid;Heterocycles;Pyridine;Pyridine Series;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Brominated heterocyclic series;compounds of pyridine;pyridine derivative;bc0001
Mol File:	4926-28-7.mol

2-Bromo-4-methylpyridine Chemical Properties

Boiling point	87 °C/10 mmHg (lit.)
density	1.545 g/mL at 25 °C (lit.)
refractive index	n20/D 1.561(lit.)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Methanol (Slightly)
pka	1.46±0.10(Predicted)
form	Liquid
color	Clear yellow
Specific Gravity	1.545
BRN	107331
InChIKey	LSZMVESSGLHDJE-UHFFFAOYSA-N
CAS DataBase Reference	4926-28-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-36-36/37/39
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

Provider	Language
2-Bromo-4-methylpyridine	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Bromo-4-methylpyridine Usage And Synthesis

Chemical Properties	Colorless to orange oily liqui
Uses	An intermediate of pyridinyl pyrrole compounds as proton pump inhibitors with improved gastric acid secretion suppressive activity
Uses	2-Bromo-4-methylpyridine may be used: in the total synthesis of ocular age pigment A2-E (2 equiv of retinal (vitamin A) and 1 equiv of ethanolamine) in the preparation of methoxy-2-(2-pyridyl)indoles in the preparation of 2-(2′,4′-difluorophenyl)-4-methylpyridine, via a Suzuki coupling reaction with 2,4-difluorophenylboronic acid

2-Bromo-4-methylpyridine Preparation Products And Raw materials

Raw materials	2-Hydroxy-4-methylpyridine-->acetyl hypofluorite-->2-Bromo-4-bromomethyl-pyridine-->4-Methylpyridine-->Bromoform-->4-Methylpyridin-2-amine-->4-METHYL-PYRIDINE-2-CARBOXYLIC ACID
Preparation Products	2-Bromo-4-pyridinecarboxaldehyde-->2-Bromopyridine-4-carboxylic acid-->2,2'-Bipyridine-4,4'-dicarboxylic acid-->ETHYL 2-BROMOISONICOTINATE-->4,4'-Bis(methoxycarbonly)-2,2'-bipyridine-->2-CYANO-4-METHYLPYRIDINE-->2-(2-bromopyridin-4-yl)-1-(4-fluorophenyl)ethanone

2-Bromo-4-methylpyridine 1-Hexadecylpyridinium bromide 2-BROMOPYRIDINE-4-N-METHYLCARBOXAMIDE 2-Bromo-4-ethylpyridine 2-BROMO-3,5-DICHLOROISONICOTINIC ACID 2-BROMOMETHYL-PYRIDINE Azamethiphos 3-BROMO-4-METHYLPYRIDINE 2,4,6-Collidine (2-Bromo-4-pyridinyl)-3-pyridinyl-methanone 2-Bromo-6-(cyanomethyl)-4-pyridinecarboxamide Bromine 2-Bromo-6-(methylthio)-4-pyridinecarboxamide 2-Bromo-N,N-dimethyl-4-pyridinecarboxamide 2,6-DIBROMOISONICOTINONITRILE 2,6-DIBROMO-3,5-DIFLUOROISONICOTINIC ACID 2-BROMO-ISONICOTINAMIDE 2-Bromo-4-nitropyridine

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