NERIIFOLIN

NERIIFOLIN Basic information
Product Name:NERIIFOLIN
Synonyms:14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside), 3-([6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxy)-14-hydroxy-5β-card-20(22)-enolide];NERIIFOLIN;digitoxigenin+thevetose;xy)-14-hydroxy-;(3-beta,5-beta)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide;(5beta)-3beta-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide;(17R)-3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14-hydroxy-5β,14β-carda-20(22)-enolide;17α-Neriifolin
CAS:466-07-9
MF:C30H46O8
MW:534.68
EINECS:207-372-5
Product Categories:
Mol File:466-07-9.mol
NERIIFOLIN Structure
NERIIFOLIN Chemical Properties
Melting point 218-225°C
alpha D23 -50.2° (CH3OH)
storage temp. 2-8°C
solubility Chloroform(Slightly), DMSO(Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color Pale Yellow
Safety Information
Hazard Codes T+
Risk Statements 26/27/28
Safety Statements 22-36/37/39-45
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS FH4906100
MSDS Information
NERIIFOLIN Usage And Synthesis
Uses17β-neriifolin could be considered a candidate for the treatment of hepatocellular carcinoma. It can also work as an inhibitor of hERG channel trafficking.
DefinitionChEBI: A cardenolide glycoside that is digitoxigenin in which the hydroxy goup at position 3 has been converted to its (6-deoxy-3-O-methyl-alpha-L-glucopyranoside derivative. Found in the seeds of Cerbera odollamand in Thevetia ahouia and Thevitia neriifolia.
NERIIFOLIN Preparation Products And Raw materials
NERIIFOLIN cerberin 6-Deoxy-L-glucose DIGITOXIGENIN

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