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| | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Basic information |
| Product Name: | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid | | Synonyms: | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14 | | CAS: | 291775-59-2 | | MF: | C12H19NO4 | | MW: | 241.28 | | EINECS: | 808-164-2 | | Product Categories: | Pharmaceuticalintermediates | | Mol File: | 291775-59-2.mol | ![(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Structure](CAS/GIF/291775-59-2.gif) |
| | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties |
| Melting point | 147-152 °C | | Boiling point | 371.0±25.0 °C(Predicted) | | density | 1.232±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 4.05±0.20(Predicted) | | optical activity | [α]22/D -170±10°, c = 1 in chloroform | | InChIKey | IFAMSTPTNRJBRG-YIZRAAEISA-N |
| | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Usage And Synthesis |
| Uses | (1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants. |
| | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Preparation Products And Raw materials |
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