4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Basic information
Product Name:4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
Synonyms:4-(chloromethyl)-2,2-dimethyl-3-dioxolane;4-chloromethyl-2,2-dimethyl-3-dioxolane;4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE;4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3- DIOXOLANE 99%;2,2-Dimethyl-4-(chloromethyl)-1,3-dioxolane;4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane,99%;1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-
CAS:4362-40-7
MF:C6H11ClO2
MW:150.6
EINECS:224-452-5
Product Categories:Organic Building Blocks;Oxygen Compounds;Protected Alcohols/Phenols
Mol File:4362-40-7.mol
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Structure
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Chemical Properties
Boiling point 156-158 °C(lit.)
density 1.063 g/mL at 25 °C(lit.)
refractive index n20/D 1.434(lit.)
Fp 128 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Oil
color Colourless
Stability:Volatile
CAS DataBase Reference4362-40-7
EPA Substance Registry System1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl- (4362-40-7)
Safety Information
Hazard Codes T
Risk Statements 10-25
Safety Statements 16-23-26-36/37/39
RIDADR UN 1992 3/PG 3
WGK Germany 3
RTECS JH6950000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Usage And Synthesis
Chemical Propertiesclear colourless to light yellow liquid
Uses4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is used in biosynthetic preparations.
Uses4-Chloromethyl-2,2-dimethyl-1,3-dioxolane may be used in the preparation of 2,2-dimethyl-4-methylene-1,3-dioxolane via dehydrochlorination.
Synthesis Reference(s)Canadian Journal of Chemistry, 44, p. 1331, 1966 DOI: 10.1139/v66-199
General Description4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a ketal that can be synthesized by the reaction of 3-chloro-propane-1,2-diol (3-MCPD) with acetone in the presence of p-toluene sulfonic acid.
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Preparation Products And Raw materials
Raw materialsEpichlorohydrin-->2-Methoxypropene-->Acetone-->2,2-Dimethoxypropane-->2,2-Dimethyl-1,3-dioxolane-4-methanol-->3-Chloro-1,2-propanediol
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE 2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.11]HEXADECANE 3-CHLORO-3-DEOXY-1,2:5,6-DIISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane 4-CHLOROMETHYL-2-ISOBUTYL-2-METHYL-[1,3]DIOXOLANE 2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.4]NONANE ALPHA-CHLORO-2,3,5,6-DIISOPROPYLIDENE-D-MANNOSE 3-CHLORO-3-DEOXY-1:2,5:6-DIISOPROPYLIDENE-D-GLUCOPYRANOSE 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE,(R)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

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