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| | Triptonide Basic information |
| Product Name: | Triptonide | | Synonyms: | TRIPTONIDE;TRIPTONIDE(PRIMARY STANDARD);NSC 165677;PG 492;(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione;14-Deoxy-14-oxotriptolide;Triptolide,14-deoxy-14-oxo;Triptonide, 98%, from Peucedanum praeruptorum Dunn | | CAS: | 38647-11-9 | | MF: | C20H22O6 | | MW: | 358.39 | | EINECS: | | | Product Categories: | Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 38647-11-9.mol |  |
| | Triptonide Chemical Properties |
| Melting point | 251～252℃ | | Boiling point | 581.1±50.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Dichloromethane (Slightly), Methanol (Slightly) | | form | Solid | | color | Off-White to Pale Beige |
| | Triptonide Usage And Synthesis |
| Uses | Triptonide is a Triptolide (T815600) analogue used in the preparation of cytotoxic fluorinated Triptolide. | | Definition | ChEBI: Triptonide is a diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. It has a role as an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent. It is a cyclic ketone, an organic heteroheptacyclic compound, a diterpene triepoxide and a butenolide. | | target | ERK | IL Receptor | GSK-3 | p38MAPK | Wnt/β-catenin |
| | Triptonide Preparation Products And Raw materials |
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