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| | 2,4-Diamino-6-hydroxypyrimidine Basic information |
| Product Name: | 2,4-Diamino-6-hydroxypyrimidine | | Synonyms: | TIMTEC-BB SBB004252;2,4-DIAMINOPYRIMIDIN-6-OL;2,4-DIAMINO-6-HYDROXYPYRIMIDINE;2,4-DIAMINO-6-PYRIMIDINOL;2,4-DIAMINO-6(1H)-PYRIMIDINONE;2,6-DIAMINO-4-PYRIMIDINOL;2,6-DIAMINO-4-PYRIMIDINONE;2,6-DIAMINOPYRIMIDIN-4-OL | | CAS: | 56-06-4 | | MF: | C4H6N4O | | MW: | 126.12 | | EINECS: | 200-254-4 | | Product Categories: | Pyrimidines;Building Blocks;PYRIMIDINE;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;APIs & Intermediate;Pyridines, Pyrimidines, Purines and Pteredines;Chemical Amines;13C & 2H Sugars;Amines;Bases & Related Reagents;Heterocycles;Nucleotides;Carbohydrates & Derivatives;bc0001;56-06-4 | | Mol File: | 56-06-4.mol |  |
| | 2,4-Diamino-6-hydroxypyrimidine Chemical Properties |
| Melting point | 285-286 °C (dec.) (lit.) | | Boiling point | 234.22°C (rough estimate) | | density | 1.3659 (rough estimate) | | refractive index | 1.7990 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 10.61±0.50(Predicted) | | form | Fine Crystalline Powder | | color | White to cream | | Sensitive | Light Sensitive | | Merck | 14,2981 | | BRN | 125006 | | InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N | | CAS DataBase Reference | 56-06-4(CAS DataBase Reference) | | NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) | | EPA Substance Registry System | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-36-26 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29335995 |
| | 2,4-Diamino-6-hydroxypyrimidine Usage And Synthesis |
| Description | 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types. | | Chemical Properties | White Solid | | Uses | 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical] | | Uses | It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan | | Uses | 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis. | | storage | +4°C | | Purification Methods | It recrystallises from H2O. [Beilstein 25 III/IV 3642.] |
| | 2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials |
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