2',5'-Difluoroacetophenone

2',5'-Difluoroacetophenone Basic information
Product Name:2',5'-Difluoroacetophenone
Synonyms:TIMTEC-BB SBB006573;2',5'-DIFLUOROACETOPHENONE;2,5-DIFLUOROACETOPHENONE;1-(2,5-Difluorophenyl)ethanone;Ethanone, 1-(2,5-difluorophenyl)-;1-(2,5-difluorophenyl)ethan-1-one;2',5'-Difluoroacetophenone 98%;2',5'-Difluoroacetophenone98%
CAS:1979-36-8
MF:C8H6F2O
MW:156.13
EINECS:217-837-4
Product Categories:Acetophenone series;Aryl Fluorinated Building Blocks;Building Blocks;C7 to C8;C7-C8;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;C7 to C8;Carbonyl Compounds;Ketones;Boronic Acid series;Aromatic Acetophenones & Derivatives (substituted)
Mol File:1979-36-8.mol
2',5'-Difluoroacetophenone Structure
2',5'-Difluoroacetophenone Chemical Properties
Boiling point 78-80°C 12mm
density 1.233 g/mL at 25 °C(lit.)
refractive index n20/D 1.4882(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Oil
color Clear Yellow
Specific Gravity1.233
BRN 2963573
InChIKeyHLAFIZUVVWJAKL-UHFFFAOYSA-N
CAS DataBase Reference1979-36-8(CAS DataBase Reference)
NIST Chemistry Reference2',5'-Difluoroacetophenone(1979-36-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29147000
MSDS Information
ProviderLanguage
1-(2,5-Difluorophenyl)ethan-1-one English
SigmaAldrich English
ACROS English
ALFA English
2',5'-Difluoroacetophenone Usage And Synthesis
Chemical Propertiesclear colorless to yellow liquid
Uses2′,5′-Difluoroacetophenone has been used in the preparation of 2,5-difluorostyrene.
Uses2',5'-Difluoroacetophenone is used in the synthesis of pyrazole compounds as inhibitors of dipeptidyl peptidases. These compounds have been shown to produce anti-hyperglycemic effects.
2',5'-Difluoroacetophenone Preparation Products And Raw materials
Preparation Products2,5-Difluorobenzoic acid-->2,5-DIFLUOROPHENACYL BROMIDE-->2-PROPEN-1-ONE, 1-(2,5-DIFLUOROPHENYL)-3-PHENYL-, (2E)-
2',5'-Difluoroacetophenone 2',3',5'-TRIFLUOROPROPIOPHENONE 2'',3'',5''-TRIFLUOROACETOPHENONE 2',4',5'-Trifluoroacetophenone 2,4,5-TRIFLUOROBENZOPHENONE 2',5'-DIFLUOROPROPIOPHENONE Trifluoroacetophenone 4'-CHLORO-2',5'-DIFLUOROACETOPHENONE,4-CHLORO-2,5-DIFLUOROACETOPHENONE 2',3',6'-TRIFLUOROACETOPHENONE 2',4',5'-TRIFLUOROPROPIOPHENONE 2',3',6'-TRIFLUOROPROPIOPHENONE 2-Bromoacetophenone 2',3',4',5',6'-PENTAFLUOROACETOPHENONE 2-(1H-1,2,4-TRIAZOL)-2',4'-DIFLUOROACETOPHENONE 2,6-DIFLUOROACETOPHENONE,2',6'-DIFLUOROACETOPHENONE 2-Phenylacetophenone 2,3,5-TRIFLUOROBENZOPHENONE PIPERACETAZINE (250 MG)

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