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| | Prunetin Basic information |
| Product Name: | Prunetin | | Synonyms: | 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4-benzopyrone;4’,5-dihydroxy-7-methoxy-isoflavon;5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4h-1-benzopyran-4-on;5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4h-1-benzopyran-4-one;5-Hydroxy-3-(4-hydroxyphenyl)-7-methoxychromen-4-one;3-(p-Hydroxyphenyl)-5-hydroxy-7-methoxychromone;PRUNASIN(RG)(PLEASE CALL);PadMakastein | | CAS: | 552-59-0 | | MF: | C16H12O5 | | MW: | 284.26 | | EINECS: | 209-018-5 | | Product Categories: | Iso-Flavones | | Mol File: | 552-59-0.mol |  |
| | Prunetin Chemical Properties |
| Melting point | 240-242°C | | Boiling point | 346.76°C (rough estimate) | | density | 1.2160 (rough estimate) | | refractive index | 1.6200 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 6.35±0.20(Predicted) | | BRN | 292155 | | LogP | 3.530 (est) | | CAS DataBase Reference | 552-59-0(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | DJ3100050 | | F | 10 |
| | Prunetin Usage And Synthesis |
| Uses | Prunetin is isoflavone with diverse biological activities. Prunetin is an antagonist of the progesterone receptor when used at concentrations of 25 and 50 μM. | | Definition | ChEBI: A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. | | Enzyme inhibitor | This Prunus species isoflavone (FW = 284.27 g/mol; CAS 552-59-0; melting point = 240°C), also known as 4’,5-dihydroxy-7- methoxyisoflavone and 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-1- benzopyran-4-one, inhibits alcohol dehydrogenase, aldehyde dehydrogenase, 3’,5’-cyclic-nucleotide phosphodiesterase, phosphodiesterase 4, and protein-tyrosine kinase. Its 4’-glucoside is prunitrin. Methylated isoflavones, such as prunetin, are rapidly converted by CYP1A2 to more active genistein and daidzein, which inhibit.formation of acetaminophen from phenacetin with an IC50 value of 16 μM. |
| | Prunetin Preparation Products And Raw materials |
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