ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Hydroxypyridine 2-Hydroxy-4-methylpyridine

2-Hydroxy-4-methylpyridine

2-Hydroxy-4-methylpyridine Basic information
Product Name:2-Hydroxy-4-methylpyridine
Synonyms:2-HYDROXY-4-PICOLINE;4-METHYL-2(1H)-PYRIDINONE;4-METHYL-2(1H)-PYRIDONE;4-METHYL-PYRIDIN-2-OL;4-METHYL-2-PYRIDINOL;4-METHYL-2-PYRIDONE;2-HYDROXY-4-METHYLPYRIDINE 97%;2-Hydroxy-4-Piocoline
CAS:13466-41-6
MF:C6H7NO
MW:109.13
EINECS:627-289-1
Product Categories:Heterocycle-Pyridine series;Pyridines;Pyridine;Pyridine Series;pharmacetical
Mol File:13466-41-6.mol
2-Hydroxy-4-methylpyridine Structure
2-Hydroxy-4-methylpyridine Chemical Properties
Melting point 131-134 °C (lit.)
Boiling point 186-187 °C/12 mmHg (lit.)
density 1.1143 (rough estimate)
refractive index 1.5444 (estimate)
Fp 186-187°C/12mm
storage temp. Inert atmosphere,Room Temperature
pkapK1:4.529(＋1) (25°C)
form powder to crystal
color White to Gray to Brown
BRN 107082
InChIKeyYBDRFJXGJQULGH-UHFFFAOYSA-N
CAS DataBase Reference13466-41-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-40
Safety Statements 26-37/39-36-22
WGK Germany 3
HS Code 29333995
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2-Hydroxy-4-methylpyridine Usage And Synthesis
Chemical Propertiesoff-white to light brown crystalline powder
Uses2-Hydroxy-4-methylpyridine is an intermediate used to prepare oxobenzopyrancarboxylate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino)(pyridinyloxy)pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists.
DefinitionChEBI: 2-Hydroxy-4-methylpyridine is a member of methylpyridines.
2-Hydroxy-4-methylpyridine Preparation Products And Raw materials
Preparation Products2-Bromo-4-methylpyridine-->5-iodo-4-Methylpyridin-2-ol-->1,4-Dimethyl-1,2-dihydropyridine-2-one
2-Hydroxy-4-methylpyridine 7-amino-4-methyl-1,8-naphthyridin-2-ol Citrazinic acid 3-Cyano-2,6-dihydroxy-4-methylpyridine 2-Hydroxy-4-methyl-5-nitropyridine Parathion-methyl 2-Hydroxy-4-methyl-3-nitropyridine Tribenuron methyl Azamethiphos 2-Hydroxy-6-methylpyridine Kresoxim-methyl Thiophanate-methyl 2-Hydroxypyridine Dibucaine hydrochloride Methyl acetate Methyl bromide CHLOROPHOSPHONAZO III METSULFURON METHYL
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