2-Aminonicotinic acid

2-Aminonicotinic acid Basic information

Product Name:	2-Aminonicotinic acid
Synonyms:	2-AMino-3-carboxypyridine;Nicotinic acid, 2-aMino- (6CI,7CI,8CI);2-Aminopyridine-3-carboxylic acid, 2-Amino-3-carboxypyridine;NSC 3049;2- aMinoacid;2-AMINO-3-PYRIDINECARBOXYLIC ACID;2-AMINOPYRIDINE-3-CARBOXYLIC ACID;2-AMINONICOTINIC ACID
CAS:	5345-47-1
MF:	C6H6N2O2
MW:	138.12
EINECS:	226-296-3
Product Categories:	Building Blocks;C6;AMINOACID;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Chemical Synthesis;Heterocyclic Building Blocks;Amines;blocks;Carboxes;Amino Acids and Derivatives;Heterocycles;Carboxylic Acids;Pyridine;Pyridines derivates;Pyridines;Carboxylic Acids;Aromatics
Mol File:	5345-47-1.mol

2-Aminonicotinic acid Chemical Properties

Melting point	295-297 °C (dec.)(lit.)
Boiling point	253.51°C (rough estimate)
density	1.3471 (rough estimate)
refractive index	1.5100 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO
pka	2.94±0.10(Predicted)
form	Crystalline Powder
color	Off-white to light yellow
Water Solubility	soluble
BRN	119031
InChIKey	KPIVDNYJNOPGBE-UHFFFAOYSA-N
CAS DataBase Reference	5345-47-1(CAS DataBase Reference)
EPA Substance Registry System	2-Aminonicotinic acid (5345-47-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-37/39-26-36
WGK Germany	3
TSCA	T
HazardClass	IRRITANT
HS Code	29333999

MSDS Information

Provider	Language
2-Aminopyridine-3-carboxylic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Aminonicotinic acid Usage And Synthesis

Chemical Properties	Off-white to light yellow crystalline powder
Uses	A component of hair dyes.
Uses	2-Aminopyridine-3-carboxylic acid can be used as: A ligand to prepare copper(II)-organic coordination compounds. A reactant to prepare pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines by reacting with trimethylsilyl cyanide and phthalaldehyde. A reactant to synthesize organo-soluble and thermally stable poly(thiourea-amide-imide) polymers.
Definition	ChEBI: An aminonicotinic acid in which the amino group is situated at position 2 of the pyridine ring.

2-Aminonicotinic acid Preparation Products And Raw materials

Raw materials	Acetic anhydride-->Ammonium hydroxide-->Zinc chloride-->Malononitrile-->1,1,3,3-Tetramethoxypropane-->2-(AMINOCARBONYL)NICOTINIC ACID-->2-Amino-3-cyanopyridine-->3-Pyridinecarboxylic acid, 2-[(phenylsulfonyl)amino]--->2-ACETAMIDO-3-PICOLINE-->2-Chloro-3-cyanopyridine-->Nicotinamide-->Nicotinic acid N-oxide-->2-Chloronicotinic acid-->Nicotinic acid-->Nicotinamide-N-oxide
Preparation Products	2-Hydroxynicotinic acid-->2-AMino-5-broMo-nicotinicacidhydrobroMide-->2-AMINO-3-CHLOROMETHYL PYRIDINE HYDROCHLORIDE

2-Aminonicotinic acid 5-Aminonicotinic acid Aminopyrine ACETAMINOPHENOL BP/USP 2-(Methylamino)pyridine-3-carboxylic acid Ethyl 2-(Chlorosulfonyl)acetate 2-Chloro-3-cyanopyridine FLUNIXIN MEGLUMINE 2-ANILINONICOTINIC ACID Niflumic acid Folic acid 2,5-PYRIDINEDICARBOXYLIC ACID 2-(ethylamino)pyridine-3-carboxylic acid Methyl 2-aminonicotinate CARBOXYLIC ACID 2-Aminopyridine 6-Aminonicotinic acid Citric acid

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