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| | Methanol-d4 Basic information |
| Product Name: | Methanol-d4 | | Synonyms: | Methanol-d4, 99.5 atom % D, for NMR;Methanol-d4, 99.6+ atom % D, for NMR;Methanol-d4, 99.8 atom % D, for NMR;Methanol-d4, contains 0.03% V/V % TMS, 99.8 atom % D, for NMR;Methanol-d4, packaged in 0.50 ml ampules, 100.0 atom % D, for NMR;Methanol-d4, packaged in 0.75 ml ampules, 100.0 atom % D, for NMR;99.96 atom % D, 99% (CP);Methanol-d4 99 atom % D | | CAS: | 811-98-3 | | MF: | CD4O | | MW: | 36.07 | | EINECS: | 212-378-6 | | Product Categories: | Analytical Chemistry;Deuterated Compounds for NMR;NMR Spectrometry;Aldrich 100% NMR Solvents for High Resolution;High Resolution NMR;Methanol-d4;Alphabetical Listings;High Throughput NMR;Labware;M;NMR;NMR Solvents;NMR Solvents and Reagents;Solvent by Application;Solvents;Solvents for High Throughput NMR;Spectroscopy Solvents (IR;Stable Isotopes;Tubes and Accessories;UV/Vis);Aldrich High Purity NMR Solvents for Routine NMR;Routine NMR | | Mol File: | 811-98-3.mol |  |
| | Methanol-d4 Chemical Properties |
| Melting point | -99 °C | | Boiling point | 65.4 °C(lit.) | | density | 0.888 g/mL at 25 °C(lit.) | | vapor pressure | 129 hPa (20 °C) | | refractive index | n20/D 1.326(lit.) | | Fp | 52 °F | | storage temp. | no restrictions. | | solubility | Chloroform (Slightly), Water (Slightly) | | form | Liquid | | color | Colorless | | Specific Gravity | 0.89 | | explosive limit | 5.5-36.5%(V) | | Water Solubility | Miscible with water, ethanol, ether, acetone and chloroform. | | BRN | 1733278 | | Exposure limits | ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3) | | Stability: | Stable. Incompatible with moisture, acids, acid chlorides, acid anhydrides, oxidizing agents, reducing agents, alkali metals. Highly flammable. | | InChIKey | OKKJLVBELUTLKV-MZCSYVLQSA-N | | CAS DataBase Reference | 811-98-3(CAS DataBase Reference) | | EPA Substance Registry System | Methanol-d4 (811-98-3) |
| Hazard Codes | F,T | | Risk Statements | 11-23/24/25-39/23/24/25 | | Safety Statements | 7-16-36/37-45 | | RIDADR | UN 1230 3/PG 2 | | WGK Germany | 1 | | RTECS | PC1400000 | | F | 10-21 | | Autoignition Temperature | 440 °C | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | II | | HS Code | 28459000 | | Toxicity | LD50 orally in Rabbit: 5628 mg/kg LD50 dermal Rabbit 17100 mg/kg |
| | Methanol-d4 Usage And Synthesis |
| Synthesis | A preparation method for providing per-deuterated methanol is provided, specifically: opening the valve of deuterium gas and carbon monoxide, and controlling the volume ratio to be 1:1 to carry out premixing (deuterium gas and carbon monoxide are respectively 2kg and 14kg, a total of 16kg). Under the pressure of 5.5MPa, at a speed of 2L/s, through the catalyst bed layer of gold oxide: platinum oxide: rhodium oxide = 1:3:2 (mass ratio) at 210~380℃, after continuous circulation reaction for 24 hours, in The per-deuterated methanol reaction solution was obtained from the separation kettle, and the obtained reaction solution was rectified to give Methanol-d4: 3.2 kg, yield 35.5%, purity 99.8%. | | Chemical Properties | colourless liquid | | Uses | Methanol-d4 may be used as a solvent to analyze the rate of exchange of methoxyl group in camphor and norcamphor dimethyl ketals. | | Application | Methyl Alcohol-d4 is the labeled analog of methyl alcohol, a common laboratory solvent used primarily in spectroscopic techniques (UV/VIS, NMR, IR). | | Definition | ChEBI: Methanol-d4 is a deuterated compound that is methanol in which all four hydrogen atoms are replaced by deuterium. It is commonly used as a solvent in NMR spectroscopy. It has a role as an amphiprotic solvent. | | General Description | Methanol-d4 (CD3OD) is a deuterated NMR solvent used for NMR-based research and analyses. It has the highest isotopic enrichment and will not interfere with the desired level of detection.
The absolute infrared absorption intensities of CD3OD have been reported between 8000 and 350cm-1. | | Synthesis | 2131312313 |
| | Methanol-d4 Preparation Products And Raw materials |
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