Tropisetron hydrochloride

Tropisetron hydrochloride Basic information

Product Name:	Tropisetron hydrochloride
Synonyms:	3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE;(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE;TROPISETRON HYDROCHLORIDE 98.5-101.5%;TropisetronHcl/Mesylate;1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1);1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride;Novaban;SDZ-ICS 930
CAS:	105826-92-4
MF:	C17H21ClN2O2
MW:	320.81
EINECS:	630-417-9
Product Categories:	Serotonin;Serotonin receptor;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;NAVOBAN;Antiemetic;zjh
Mol File:	105826-92-4.mol

Tropisetron hydrochloride Chemical Properties

Safety Information

RIDADR	2811
WGK Germany	3
HazardClass	6.1
PackingGroup	III
HS Code	29399990
Toxicity	mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998.

MSDS Information

Tropisetron hydrochloride Usage And Synthesis

Chemical Properties	White to Off-White Crystalline Solid
Uses	Specific serotonin (5-HT3) receptor antagonist. Antiemetic.
Uses	A selective 5-HT3 serotonin receptor antagonist
Definition	ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Biological Activity	Potent, orally active 5-HT 3 receptor antagonist. Antiemetic.
Biochem/physiol Actions	Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
storage	Room temperature (desiccate)

Tropisetron hydrochloride Preparation Products And Raw materials

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