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Desloratadine N-Hydroxypiperidine

Desloratadine N-Hydroxypiperidine Basic information
Product Name:Desloratadine N-Hydroxypiperidine
Synonyms:Desloratadine N-Hydroxypiperidine;8-Chloro-6,11-dihydro-11-(1-hydroxy-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;Desloratadine N-Hydroxy IMpurity;N-Hydroxy Desloratadine;Loratadine Impurity 6;Desloratadine Impurity 17;8-chloro-11-(1-hydroxypiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine;esloratadine N-Hydroxy Impurity
CAS:1193725-73-3
MF:C19H19ClN2O
MW:326.82
EINECS:
Product Categories:Amines;Aromatics;Heterocycles;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1193725-73-3.mol
Desloratadine N-Hydroxypiperidine Structure
Desloratadine N-Hydroxypiperidine Chemical Properties
Melting point >165°C (dec.)
Boiling point 515.3±50.0 °C(Predicted)
density 1.326±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka13.23±0.20(Predicted)
color Pale Orange to Brown
Stability:Hygroscopic
Safety Information
MSDS Information
Desloratadine N-Hydroxypiperidine Usage And Synthesis
Chemical PropertiesTan Solid
UsesA related compound of Desloratadine (D290250).
Desloratadine N-Hydroxypiperidine Preparation Products And Raw materials
N-BUTYL-2-PIPERIDINE CARBOXYLIC ACID Desloratadine IMpurity B Desloratadine D5 1-Ethyl-6-methyl-3-piperidinol Desloratadine IMpurity 3 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 8-Dechloro-9-chloro Desloratadine 4-Hydroxymethyl Loratadine Desloratadine Pyridine N-oxide 2-Hydroxymethyl Loratadine 3-Isobutylglutarimid 8-Dechloro-9-chloro Loratadine 5,6-Dehydro-N-methyl Desloratadine (3R,5R)-3-(Boc-amino)-5-methylpiperidine Sch 37370 3-Difluromethyl-2-oxo-3-piperdinecarboxamide
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