|
| | mexidol Basic information |
| Product Name: | mexidol | | Synonyms: | mexidol;2-Ethyl-6-methyl-3-pyridinol butanoate (1:1);2-Ethyl-6-methyl-3-hydroxypyridine succinate;Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1);Mexidole (2-ethyl-6-Methyl-3-hydroxypyridine succinate);2-Ethyl-6-Methylpyridin-3-ol succinate;2-ethyl-6-Methyl-3-hydroxypyridine succinate (Mexidole);2-Ethyl-6-Methyl-3-pyridinol butanoate | | CAS: | 127464-43-1 | | MF: | C8H11NO.C4H6O4 | | MW: | 255.268 | | EINECS: | 811-046-3 | | Product Categories: | | | Mol File: | 127464-43-1.mol |  |
| | mexidol Chemical Properties |
| Melting point | 119-120 °C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White |
| | mexidol Usage And Synthesis |
| Uses | The Chinese name of Mesidol is 2-ethyl-6methyl-3-hydroxypyridine succinic acid (Mexidox), 2-ethyl-6-methyl-3-hydroxypyridine succinate (emoxypine, product Name-MEXIDOL?, etc.) is widely used in medicine as an antioxidant and anti-hypoxic agent. Use 2-ethyl-6-methyl-3-hydroxypyridine succinate as a nootropic and anxiolytic, anti-ischemic and atherosclerotic, anti-angina, liver protection, antibacterial, etc. | | Preparation | 3.5 liters of ethanol, 1.2 kg of 2-ethyl-6-methyl-3-hydroxypyridine and 1.0 kg of succinic acid were added to the reactor. The reaction mass is heated to the boiling point of ethanol (78°C) and stirring is continued for 20 minutes until the components are completely dissolved. Then, keep the reaction mass in the reactor under stirring until the temperature reaches 20°C, cool to 5°C and keep at this temperature for 16 hours, stirring occasionally. The suspension is then stirred until the material is homogeneous, overloaded in a centrifuge and filtered. The precipitate of the succinate salt of 2-ethyl-6-methyl-3-hydroxypyridine was dried to constant weight in a vacuum oven at 45°C. The yield of the target product 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexitrad) was 89%. |
| | mexidol Preparation Products And Raw materials |
|
