2',4'-Dichloroacetophenone

2',4'-Dichloroacetophenone Basic information

Product Name:	2',4'-Dichloroacetophenone
Synonyms:	1-(2,4-dichlorophenyl)-ethanon;Methyl 2,4-dichlorophenyl ketone;2,4-Dichloracetophenone;2',4'-Dichloroacetophenone,94%;2',4'-Dichloroacetophenone,97%;2',4'-Dichloroacetop;2,4-Dicloro actophenone;2, 4 - dichlorobenzene ethyl ketone
CAS:	2234-16-4
MF:	C8H6Cl2O
MW:	189.04
EINECS:	218-780-8
Product Categories:	Carbonyl Compounds;Building Blocks;C7 to C8;Chemical Synthesis;Organic Building Blocks;The intermediate of ketoconazole;Ketones;Aromatic Acetophenones & Derivatives (substituted);Carbonyl Compounds;Acetophenone Series;C7 to C8;Adehydes, Acetals & Ketones;Chlorine Compounds;2234-16-4
Mol File:	2234-16-4.mol

2',4'-Dichloroacetophenone Chemical Properties

Melting point	33-34 °C(lit.)
Boiling point	140-150 °C15 mm Hg(lit.)
density	1.32
vapor pressure	3.2Pa at 25℃
refractive index	n20/D 1.5635(lit.)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform, Methanol (Slightly)
form	Solid
color	Colorless to yellow-brown
Water Solubility	ca. 200 mg/L
BRN	637819
InChIKey	XMCRWEBERCXJCH-UHFFFAOYSA-N
LogP	2.62 at 20℃
CAS DataBase Reference	2234-16-4(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-(2,4-dichlorophenyl)-(2234-16-4)
EPA Substance Registry System	2',4'-Dichloroacetophenone (2234-16-4)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-41-52/53-36/37/38
Safety Statements	26-39-61-36
WGK Germany	2
Hazard Note	Irritant
TSCA	Yes
HS Code	29143990

MSDS Information

Provider	Language
2',4'-Dichloroacetophenone	English
SigmaAldrich	English
ACROS	English
ALFA	English

2',4'-Dichloroacetophenone Usage And Synthesis

Chemical Properties	Colorless to yellow-brown solid
Uses	2′,4′-Dichloroacetophenone was used in the synthesis of the Schiff base derivatives.
Flammability and Explosibility	Notclassified

2',4'-Dichloroacetophenone Preparation Products And Raw materials

Raw materials

Dichloromethane-->Aluminum chloride-->Acetyl chloride-->1,3-Dichlorobenzene

Preparation Products

Itraconazole-->2,2,2',4'-TETRACHLOROACETOPHENONE-->1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE-->2,2',4'-Trichloroacetophenone-->4,4,4-TRIFLUORO-1-(2,4-DICHLOROPHENYL)-1,3-BUTANEDIONE-->(2E)-1-(2,4-dichlorophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one-->(2E)-1-(2,4-dichlorophenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one-->3-(2,4-DICHLOROPHENYL)PYRAZOLE-->[2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl benzoate-->6-chloro-2-(6-chloro-3-oxobenzo[b]thien-2(3H)-ylidene)benzo[b]thiophene-3(2H)-one

4-(2,4-DICHLOROPHENYL)-4-OXOBUTYRIC ACID 2-BROMO-2',4'-DICHLOROACETOPHENONE (2,4-DICHLOROPHENYL)[5-(DIMETHYLAMINO)-4-(4-PHENOXYPHENYL)-2-THIENYL]METHANONE 2,2,2',4'-TETRACHLOROACETOPHENONE 2-BROMO-2'',4''-DICHLOROACETOPHENONE 98%,ALPHA-BROMO-2',4'-DICHLOROACETOPHENONE 2',4'-DICHLOROPROPIOPHENONE 2',3'-Dichloroacetophenone,2,3-Dichloroacetophenone 2',6'-Dichloroacetophenone 98% (2,4-DICHLOROPHENYL)(2-PHENYL-1,3-THIAZOL-5-YL)METHANONE 2,4-Dichloro-5-fluoroacetophenone L-PICEIN 2-Bromoacetophenone (2-ANILINO-1,3-THIAZOL-5-YL)(2,4-DICHLOROPHENYL)METHANONE 2,4-DICHLORO-4'-FLUOROBENZOPHENONE 1,3-dichloro-2-methylanthraquinone 3-(8-CHLORO-4H-THIENO[3,2-C]CHROMEN-2-YL)-1-(2,4-DICHLOROPHENYL)PROP-2-EN-1-ONE 4-Amino-α-tert-butylamino-3,5-dichloroacetophenone hydrochloride [2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL](2,4-DICHLOROPHENYL)METHANONE

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