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| Product Name: | Difloxacin | | Synonyms: | DIFLOXACIN;-1-piperazinyl)-4-oxo-;3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl;a56619;6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt;Difloxacin Hydrochloride Salt;6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;DIFLOXACINHCL/MESYLATE | | CAS: | 98106-17-3 | | MF: | C21H19F2N3O3 | | MW: | 399.39 | | EINECS: | | | Product Categories: | Inhibitors;Intermediates & Fine Chemicals;Chiral Reagents;Pharmaceuticals | | Mol File: | 98106-17-3.mol |  |
| | Difloxacin Chemical Properties |
| Melting point | 279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5)) | | Boiling point | 595.5±50.0 °C(Predicted) | | density | 1.409±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | pka | 6.17±0.41(Predicted) | | form | Solid | | color | White to Pale Yellow | | CAS DataBase Reference | 98106-17-3(CAS DataBase Reference) |
| | Difloxacin Usage And Synthesis |
| Description | Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin. | | Mechanism of action | Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. | | Physical properties | Whtie-Cream to Yellowish Crystalline Powder | | Uses | Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin. | | Definition | ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall
as the monohydrochloride salt) for the treatment of bacterial infections in dogs. |
| | Difloxacin Preparation Products And Raw materials |
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