| | 1-Bromohexane Chemical Properties |
| Melting point | −85 °C(lit.) | | Boiling point | 154-158 °C(lit.) | | density | 1.176 g/mL at 25 °C(lit.) | | vapor density | 5.7 (vs air) | | vapor pressure | <10 mm Hg ( 20 °C) | | refractive index | n20/D 1.448(lit.) | | Fp | 135 °F | | storage temp. | Store below +30°C. | | solubility | <1g/l | | form | Liquid | | color | Clear | | Water Solubility | Immiscible with water. | | BRN | 1731290 | | Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. Combustible. | | InChIKey | MNDIARAMWBIKFW-UHFFFAOYSA-N | | CAS DataBase Reference | 111-25-1(CAS DataBase Reference) | | NIST Chemistry Reference | Hexane, 1-bromo-(111-25-1) | | EPA Substance Registry System | Hexane, 1-bromo- (111-25-1) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-10 | | Safety Statements | 26-36-16 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 2 | | RTECS | MO0925000 | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29033036 | | Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
| | 1-Bromohexane Usage And Synthesis |
| Chemical nature | 1-Bromohexane is organobromine compound with formula Br(CH2)5CH3. It is a colorless liquid.
 | | Synthesis and reactions | Most 1-bromoalkanes are prepared by free-radical addition of hydrogen bromide to the 1-alkene. These conditions lead to anti-Markovnikov addition, giving the 1-bromo derivative.
1-Bromohexane undergoes reactions expected of simple alkyl bromides. It can form Grignard reagents. It reacts with potassium fluoride to give the corresponding fluorocarbons.
| | Chemical Properties | 1-Bromohexane is a colourless liquid organohalide. It is a solvent that is frequently used in grignard reactions. It is also used as Intermediate, for introduction of hexyl group. | | Uses | 1-Bromohexane is utilized in the preparation of pharmaceuticals and organic chemicals. It is involved in Grignard reactions as an alkylating agent and in the synthesis of bromo-cyclic compounds. | | Application | 1-Bromohexane is a very useful synthetic intermediate，it can be used to react with Mg to prepare Grignard reagents which play an important role in formation of carbon-carbon bond. | | Synthesis Reference(s) | Chemistry Letters, 7, p. 833, 1978
Synthetic Communications, 6, p. 21, 1976 DOI: 10.1080/00397917608062128
Tetrahedron, 40, p. 641, 1984 DOI: 10.1016/S0040-4020(01)91092-0 | | Purification Methods | Shake the bromide with H2SO4, wash with water, dry (K2CO3) and fractionally distil. [Beilstein 1 IV 352.] |
| | 1-Bromohexane Preparation Products And Raw materials |
|
