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| | HYDROQUININE Basic information |
| Product Name: | HYDROQUININE | | Synonyms: | HYDROQUININE;Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8alpha,9R)-;Quinine, 10,11-dihydro-;(8S,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol;(8α,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol;(8α,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol;10,11-Dihydroquinine;Hydroquinine,Dihydroquinine | | CAS: | 522-66-7 | | MF: | C20H26N2O2 | | MW: | 326.44 | | EINECS: | 208-334-0 | | Product Categories: | | | Mol File: | 522-66-7.mol |  |
| | HYDROQUININE Chemical Properties |
| Melting point | 168-176 °C(lit.) | | alpha | D18 -142° (alc); D20 -236° (c = 0.82 in 0.1N H2SO4) | | Boiling point | 464.47°C (rough estimate) | | density | 1.1117 (rough estimate) | | refractive index | 1.6800 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly) | | form | Solid | | pka | 5.33(at 25℃) | | color | White to Off-White | | optical activity | [α]25/D 148°, c = 1 in ethanol | | Water Solubility | 99.99mg/L(20 ºC) | | Merck | 13,4832 | | BRN | 91444 | | InChIKey | LJOQGZACKSYWCH-WGFDLZGGSA-N | | LogP | 3.770 (est) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | 1544 | | WGK Germany | 3 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29339900 |
| | HYDROQUININE Usage And Synthesis |
| Chemical Properties | Solid | | Uses | (-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties. | | Definition | ChEBI: Hydroquinine is a cinchona alkaloid. | | Purification Methods | Hydroquinine [522-66-7] M 326.4, m 168-171o, 171.5o, [ ] D-143o (c 1.087, EtOH), 5.33 and 8.87. Recrystallise hydroquinine from EtOH, Et2O or *C6H6. [Rabe & Schultz Chem Ber 66 120 1933, Beilstein 23 III/IV 3193, 23/13 V 340.] |
| | HYDROQUININE Preparation Products And Raw materials |
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