ChemicalBook Product Catalog Organic Chemistry Amides Naphthenic amines derivatives 4-BROMO-2-METHOXY-PHENYLAMINE

4-BROMO-2-METHOXY-PHENYLAMINE

4-BROMO-2-METHOXY-PHENYLAMINE Basic information
Product Name:4-BROMO-2-METHOXY-PHENYLAMINE
Synonyms:4-BROMO-2-METHOXY-PHENYLAMINE;4-BROMO-2-METHOXYANILINE;4-BROMO-2-METHOXYANILINE[2-AMINO-5-BROMOANISOLE];2-Amino-5-bromoanisole;4-bromo-o-anisidine;4-Bromo-o-anisidine 2-Amino-5-bromoanisole;4-Bromo-2-methoxyaniline 99%;2-Amino-5-bromoanisole, 4-Bromo-o-anisidine
CAS:59557-91-4
MF:C7H8BrNO
MW:202.05
EINECS:200-002-4
Product Categories:C2 to C8;Amines;Building Blocks;C7;Chemical Synthesis;Ethers;Aniline;New Products for Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Oxygen Compounds
Mol File:59557-91-4.mol
4-BROMO-2-METHOXY-PHENYLAMINE Structure
4-BROMO-2-METHOXY-PHENYLAMINE Chemical Properties
Melting point 59 °C
Boiling point 250.4±20.0 °C(Predicted)
density 1.531±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in methanol.
pka3.83±0.10(Predicted)
form solid
color White to Orange to Green
InChIKeyWRFYIYOXJWKONR-UHFFFAOYSA-N
CAS DataBase Reference59557-91-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-43-52
Safety Statements 36/37
RIDADR UN2811/6.1/IIIPG
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 2922290090
MSDS Information
4-BROMO-2-METHOXY-PHENYLAMINE Usage And Synthesis
Chemical PropertiesBlack particles
Uses4-Bromo-2-methoxyaniline is used as a reagent in the synthesis of 3,5-diamino-1,2,4-triazole ureas as potent anaplastic lymphoma kinase (ALK) inhibitors. It is also used as a reagent in the synthesis of chroman-3-amides as potent Rho kinase inhibitors. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Synthesis Reference(s)Journal of Medicinal Chemistry, 32, p. 1936, 1989 DOI: 10.1021/jm00128a041
4-BROMO-2-METHOXY-PHENYLAMINE Preparation Products And Raw materials
Preparation Products5-BROMO-2-CHLOROANISOLE-->4-Bromo-2-methoxyphenylboronic acid-->2-Benzoxazolecarboxylic acid, 4-broMo-, ethyl ester
5-(((4-BROMO-2,5-DIMETHOXYPHENYL)AMINO)METHYLENE)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE DIBROMOBAPTA bromchlorenone 4-BROMO-2-METHOXY-PHENYLAMINE 6-BROMO-BENZOXAZOLINONE 2-Benzoxazolinone, 6-bromo-5-chloro-3-(3-chloropropyl)- AURORA 4406 3-BROMO-5-METHOXY-2,6-DINITRO-BENZOIC ACID METHYL ESTER 3-BROMO-5-BENZYLOXY-2,6-DINITROBENZOIC ACID BENZYL ESTER 2-(((4-BROMO-2,5-DIMETHOXYPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE AURORA 4408 AURORA 4459 TIMTEC-BB SBB007586 AURORA 4585 2,4-DIBROMO-6-(DIFLUOROMETHOXY)ANILINE 4-BROMO-2-(TRIFLUOROMETHOXY)PHENYL ISOTHIOCYANATE 4-Bromo-2-trifluoromethoxyaniline 4-BROMO-2-(TRIFLUOROMETHOXY)ACETANILIDE
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